GSK1904529A - Small Molecule (ID:10134-101)
| HMS LINCS ID: |
10134-101
|
| Name: | GSK1904529A |
| Alternative Names: | |
| LINCS ID: | LSM-1134 |
| PubChem CID: | 25124816 |
| ChEBI ID: | |
| ChEMBL ID: | 466397 |
| Molecular Mass: | 851.34 |
| InChi: | InChI=1S/C44H47F2N9O5S/c1-5-28-26-35(38(60-3)27-36(28)53-19-15-30(16-20-53)52-21-23-54(24-22-52)61(4,57)58)49-44-47-17-14-34(48-44)42-40(50-39-11-6-7-18-55(39)42)29-12-13-37(59-2)31(25-29)43(56)51-41-32(45)9-8-10-33(41)46/h6-14,17-18,25-27,30H,5,15-16,19-24H2,1-4H3,(H,51,56)(H,47,48,49) |
| InChi Key: | MOSKATHMXWSZTQ-UHFFFAOYSA-N |
| SMILES: | CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
IGF1R, INSR | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | AIM1, AURKA, AURKB, LCK |
10 (confirmed non-binding) |
Batch Information for HMSL10134-101-3:
| HMS LINCS Batch ID: | 10134-101-3 |
| Provider: | MedChem Express |
| Provider Batch ID: | 03710 |
| Salt: | 101 |
| Molecular Formula: | C44H47F2N9O5S |
| Molecular Weight: | 851.96 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-06-17 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10134-101-3:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10134-101-3_LCMS.pdf |
(Kd <100 nM)