PI103 - Small Molecule (ID:10126-102)

HMS LINCS ID: 10126-102
Name: PI103
Alternative Names:
LINCS ID: LSM-1126
PubChem CID: 9884685
ChEBI ID:
ChEMBL ID: 538346
Molecular Mass: 348.12
InChi: InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2
InChi Key: TUVCWJQQGGETHL-UHFFFAOYSA-N
SMILES: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
FKBP1A, MTOR, PIK3C2B, PIK3C2G, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PRKDC
2
(equivalent to 100 nM ≤ Kd < 1µM)
DAPK3, HIPK2, HIPK3, MAP3K19, PIP4K2C, RIOK2
3
(equivalent to 1µM ≤ Kd < 10 µM)
BRAF, CDC42BPA, CDK1, CDK7, CHUK, CLK1, CLK2, CLK3, CSNK2A1, CSNK2A2, DAPK1, DAPK2, DYRK1B, DYRK2, FLT3, HIPK1, HIPK4, IRAK1, JAK1, LIMK2, MAPK13, MINK1, MYLK, PI4KB, PIK3C2A, PRKCG, PRKCZ, RAF1, SGK2, TYK2
10
(confirmed non-binding)
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Batch Information for HMSL10126-102-4:

HMS LINCS Batch ID: 10126-102-4
Provider: MedChem Express
Provider Batch ID: 05624
Salt: 102
Molecular Formula: C19H17ClN4O3
Molecular Weight: 384.82
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-06-17
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10126-102-4:

Date HMS QC Outcome Comment Files
08/31/2015 PASS HMSL10126-102-4_LCMS.pdf