Kin237 - Small Molecule (ID:10113-101)

HMS LINCS ID: 10113-101
Name: Kin237
Alternative Names: Kin001-237; c-Met/Ron dual kinase inhibitor
LINCS ID: LSM-1113
PubChem CID: 16757524
ChEBI ID:
ChEMBL ID:
Molecular Mass: 556.21
InChi: InChI=1S/C31H29FN4O5/c1-19-28(30(38)36(21-8-6-5-7-9-21)35(19)18-31(2,3)39)29(37)34-20-10-13-27(24(32)16-20)41-26-14-15-33-25-17-22(40-4)11-12-23(25)26/h5-17,39H,18H2,1-4H3,(H,34,37)
InChi Key: UYMSIPINLJNNOU-UHFFFAOYSA-N
SMILES: CC1=C(C(=O)N(N1CC(C)(C)O)C2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
MET
2
(equivalent to 100 nM ≤ Kd < 1µM)
IGF1R, MST1R
3
(equivalent to 1µM ≤ Kd < 10 µM)
KDR

Batch Information for HMSL10113-101-1:

HMS LINCS Batch ID: 10113-101-1
Provider: Calbiochem
Provider Batch ID:
Salt: 101
Molecular Formula: C31H29FN4O5
Molecular Weight: 556.58
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-12-02

HMS QC Testing Events for HMSL10113-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10113-101-1_LCMS.pdf
01/10/2012 PASS None