MG-132 - Small Molecule (ID:10107-101)
| HMS LINCS ID: |
10107-101
|
| Name: | MG-132 |
| Alternative Names: | |
| LINCS ID: | LSM-1107 |
| PubChem CID: | 462382 |
| ChEBI ID: | |
| ChEMBL ID: | 64925 |
| Molecular Mass: | 475.30 |
| InChi: | InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1 |
| InChi Key: | TZYWCYJVHRLUCT-VABKMULXSA-N |
| SMILES: | CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
CTSB, CTSK, PSMB5 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | PSMB1, PSMB2 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | NFKBIA |
Batch Information for HMSL10107-101-4:
| HMS LINCS Batch ID: | 10107-101-4 |
| Provider: | MedChem Express |
| Provider Batch ID: | 17032 |
| Salt: | 101 |
| Molecular Formula: | C26H41N3O5 |
| Molecular Weight: | 475.62 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-09-04 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10107-101-4:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 09/03/2015 | PASS | HMSL10107-101-4_NMR.pdf, HMSL10107-101-4_LCMS.pdf |
(Kd <100 nM)