JNK-9L - Small Molecule (ID:10100-101)

HMS LINCS ID: 10100-101
Name: JNK-9L
Alternative Names: KIN001-204
LINCS ID: LSM-36386
PubChem CID: 25222038
ChEBI ID:
ChEMBL ID:
Molecular Mass: 502.22
InChi: InChI=1S/C26H27FN8O2/c27-20-15-19(16-23(17-20)33-7-11-36-12-8-33)24-5-6-28-25(31-24)30-21-1-3-22(4-2-21)35-18-29-26(32-35)34-9-13-37-14-10-34/h1-6,15-18H,7-14H2,(H,28,30,31)
InChi Key: AHMHIFXJPSHHPH-UHFFFAOYSA-N
SMILES: C1COCCN1C2=CC(=CC(=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5C=NC(=N5)N6CCOCC6)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
Mapk10, MAPK8, MAPK9
2
(equivalent to 100 nM ≤ Kd < 1µM)
JAK2, MAPK10
10
(confirmed non-binding)
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Batch Information for HMSL10100-101-1:

HMS LINCS Batch ID: 10100-101-1
Provider: Nathanael Gray (DFCI)
Provider Batch ID: JNK-9L-1
Salt: 101
Molecular Formula: C26H27FN8O2
Molecular Weight: 502.54
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10100-101-1:

Date HMS QC Outcome Comment Files
03/13/2015 PASS HMSL10100-101-1_LCMS.pdf