JNK-9L - Small Molecule (ID:10100-101)
HMS LINCS ID: | 10100-101 |
Name: | JNK-9L |
Alternative Names: | KIN001-204 |
LINCS ID: | LSM-36386 |
PubChem CID: | 25222038 |
ChEBI ID: | |
ChEMBL ID: | |
Molecular Mass: | 502.22 |
InChi: | InChI=1S/C26H27FN8O2/c27-20-15-19(16-23(17-20)33-7-11-36-12-8-33)24-5-6-28-25(31-24)30-21-1-3-22(4-2-21)35-18-29-26(32-35)34-9-13-37-14-10-34/h1-6,15-18H,7-14H2,(H,28,30,31) |
InChi Key: | AHMHIFXJPSHHPH-UHFFFAOYSA-N |
SMILES: | C1COCCN1C2=CC(=CC(=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5C=NC(=N5)N6CCOCC6)F |
Relevant Citations: | |
Comments: | |
Date Publicly Available: | |
Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)Target Affinity Spectrum Value | HUGO Gene Name |
---|---|
Mapk10, MAPK8, MAPK9 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | JAK2, MAPK10 |
10 (confirmed non-binding) |
Batch Information for HMSL10100-101-1:
HMS LINCS Batch ID: | 10100-101-1 |
Provider: | Nathanael Gray (DFCI) |
Provider Batch ID: | JNK-9L-1 |
Salt: | 101 |
Molecular Formula: | C26H27FN8O2 |
Molecular Weight: | 502.54 |
Purity: | |
Purification Method: | |
Chemical Synthesis Reference: | |
Comments: | |
Date Publicly Available: | 2011-07-15 |
Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10100-101-1:
Date | HMS QC Outcome | Comment | Files |
---|---|---|---|
03/13/2015 | PASS | HMSL10100-101-1_LCMS.pdf |
(Kd <100 nM)