WZ-4-145 - Small Molecule (ID:10082-101)

HMS LINCS ID: 10082-101
Name: WZ-4-145
Alternative Names:
LINCS ID: LSM-5545
PubChem CID:
ChEBI ID:
ChEMBL ID:
Molecular Mass: 690.22
InChi: InChI=1S/C34H36Cl2N8O4/c1-5-30(45)40-24-8-6-22(7-9-24)20-44(34(46)41-33-31(35)26(47-3)18-27(48-4)32(33)36)29-19-28(37-21-38-29)39-23-10-12-25(13-11-23)43-16-14-42(2)15-17-43/h5-13,18-19,21H,1,14-17,20H2,2-4H3,(H,40,45)(H,41,46)(H,37,38,39)
InChi Key: SFLKJNSBBVSPFE-UHFFFAOYSA-N
SMILES: O=C(NC1=C(Cl)C(OC)=CC(OC)=C1Cl)N(CC2=CC=C(NC(C=C)=O)C=C2)C3=CC(NC4=CC=C(N5CCN(C)CC5)C=C4)=NC=N3
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
BLK, CSF1R, DDR1, EGFR, FGFR4, FLT4, PDGFRA, PDGFRB, STK10, TIE1
10
(confirmed non-binding)
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Batch Information for HMSL10082-101-1:

HMS LINCS Batch ID: 10082-101-1
Provider: Nathanael Gray (DFCI)
Provider Batch ID: WZ-4-145-1
Salt: 101
Molecular Formula: C34H36Cl2N8O4
Molecular Weight: 691.61
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10082-101-1:

Date HMS QC Outcome Comment Files
03/13/2015 PASS HMSL10082-101-1_LCMS.pdf
06/06/2011 PASS None