KU55933 - Small Molecule (ID:10074-101)
| HMS LINCS ID: |
10074-101
|
| Name: | KU55933 |
| Alternative Names: | |
| LINCS ID: | LSM-1074 |
| PubChem CID: | 5278396 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 395.06 |
| InChi: | InChI=1S/C21H17NO3S2/c23-14-12-16(25-20(13-14)22-8-10-24-11-9-22)15-4-3-7-19-21(15)27-18-6-2-1-5-17(18)26-19/h1-7,12-13H,8-11H2 |
| InChi Key: | XRKYMMUGXMWDAO-UHFFFAOYSA-N |
| SMILES: | C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ATM | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | DYRK1A, GSK3B, MAP3K11, MAPK15, PIM1, PIM3 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MTOR, PRKDC |
10 (confirmed non-binding) |
Batch Information for HMSL10074-101-1:
| HMS LINCS Batch ID: | 10074-101-1 |
| Provider: | Tocris |
| Provider Batch ID: | 3544-1 |
| Salt: | 101 |
| Molecular Formula: | C21H17NO3S2 |
| Molecular Weight: | 395.49 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2011-07-15 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10074-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 03/13/2015 | PASS | HMSL10074-101-1_LCMS.pdf | |
| 06/06/2011 | PASS | None |
(Kd <100 nM)