GSK1070916 - Small Molecule (ID:10062-101)
| HMS LINCS ID: |
10062-101
|
| Name: | GSK1070916 |
| Alternative Names: | KIN001-216 |
| LINCS ID: | LSM-1062 |
| PubChem CID: | 46885626 |
| ChEBI ID: | |
| ChEMBL ID: | 1090479 |
| Molecular Mass: | 507.27 |
| InChi: | InChI=1S/C30H33N7O/c1-6-37-19-26(28(34-37)21-10-12-23(13-11-21)32-30(38)36(4)5)24-14-15-31-29-25(24)17-27(33-29)22-9-7-8-20(16-22)18-35(2)3/h7-17,19H,6,18H2,1-5H3,(H,31,33)(H,32,38) |
| InChi Key: | QTBWCSQGBMPECM-UHFFFAOYSA-N |
| SMILES: | CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
AIM1, AURKB, AURKC, FGFR1, FLG, FLT1, FLT4, SIK1, TEK | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | AURKA |
Batch Information for HMSL10062-101-3:
| HMS LINCS Batch ID: | 10062-101-3 |
| Provider: | |
| Provider Batch ID: | |
| Salt: | 101 |
| Molecular Formula: | |
| Molecular Weight: | |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2012-11-14 |
| Most Recent Update: | 2016-12-02 |
(Kd <100 nM)