CG-930 - Small Molecule (ID:10058-101)
| HMS LINCS ID: |
10058-101
|
| Name: | CG-930 |
| Alternative Names: | JNK930 |
| LINCS ID: | LSM-1058 |
| PubChem CID: | 57394468 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 448.18 |
| InChi: | InChI=1S/C21H23F3N6O2/c22-11-7-15(23)18(16(24)8-11)28-21-27-17-9-25-20(26-12-1-3-14(31)4-2-12)29-19(17)30(21)13-5-6-32-10-13/h7-9,12-14,31H,1-6,10H2,(H,27,28)(H,25,26,29)/t12?,13-,14?/m1/s1 |
| InChi Key: | IBGLGMOPHJQDJB-ROKHWSDSSA-N |
| SMILES: | C1COC[C@@H]1N2C3=NC(=NC=C3N=C2NC4=C(C=C(C=C4F)F)F)NC5CCC(CC5)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MAPK10, MAPK8, MAPK9 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | EGFR, MAPK3 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAPK14 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20114 | CG-930 KINOMEscan | KINOMEscan |
KINOMEscan Image
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10058-101-1 | Nathanael Gray (DFCI) | JNK-930-1 |
(Kd <100 nM)