BX-912 - Small Molecule (ID:10055-101)

HMS LINCS ID: 10055-101
Name: BX-912
Alternative Names:
LINCS ID: LSM-1055
PubChem CID: 11754511
ChEBI ID:
ChEMBL ID:
Molecular Mass: 470.12
InChi: InChI=1S/C20H23BrN8O/c21-17-12-24-19(28-18(17)23-7-6-16-11-22-13-25-16)26-14-4-3-5-15(10-14)27-20(30)29-8-1-2-9-29/h3-5,10-13H,1-2,6-9H2,(H,22,25)(H,27,30)(H2,23,24,26,28)
InChi Key: DMMILYKXNCVKOJ-UHFFFAOYSA-N
SMILES: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
AURKB, AURKC, BMP2K, BMPR2, CSNK2A2, FLT3, FLT4, IRAK4, JAK2, JAK3, LATS2, MAP3K10, MAP3K19, MAPK10, MARK4, MKNK2, MYLK3, NIM1K, NUAK1, PDGFRA, PDGFRB, PDPK1, PRKCE, RET, RIOK1, TAOK3, TYK2, ULK1, ULK3
10
(confirmed non-binding)
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Batch Information for HMSL10055-101-1:

HMS LINCS Batch ID: 10055-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HY-999-20101004
Salt: 101
Molecular Formula: C20H23BrN8O
Molecular Weight: 471.35
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10055-101-1:

Date HMS QC Outcome Comment Files
03/13/2015 PASS HMSL10055-101-1_LCMS.pdf
02/22/2011 PASS None