Sirolimus - Small Molecule (ID:10052-101)
| HMS LINCS ID: |
10052-101
|
| Name: | Sirolimus |
| Alternative Names: | Rapamycin |
| LINCS ID: | LSM-1052 |
| PubChem CID: | 5040 |
| ChEBI ID: | |
| ChEMBL ID: | 413 |
| Molecular Mass: | 913.56 |
| InChi: | InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3 |
| InChi Key: | QFJCIRLUMZQUOT-UHFFFAOYSA-N |
| SMILES: | CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
EIF4E, FKBP1A, FKBP1B, FKBP5, FKBP9, MTOR |
Batch Information for HMSL10052-101-3:
| HMS LINCS Batch ID: | 10052-101-3 |
| Provider: | LC Laboratories |
| Provider Batch ID: | |
| Salt: | 101 |
| Molecular Formula: | C51H79NO13 |
| Molecular Weight: | 914.17 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2012-11-14 |
| Most Recent Update: | 2016-12-02 |
(Kd <100 nM)