Sirolimus - Small Molecule (ID:10052-101)

HMS LINCS ID: 10052-101
Name: Sirolimus
Alternative Names: Rapamycin
LINCS ID: LSM-1052
PubChem CID: 5040
ChEBI ID:
ChEMBL ID: 413
Molecular Mass: 913.56
InChi: InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3
InChi Key: QFJCIRLUMZQUOT-UHFFFAOYSA-N
SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
EIF4E, FKBP1A, FKBP1B, FKBP5, FKBP9, MTOR

Batch Information for HMSL10052-101-1:

HMS LINCS Batch ID: 10052-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HM-039-20100323
Salt: 101
Molecular Formula: C51H79NO13
Molecular Weight: 914.17
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10052-101-1:

Date HMS QC Outcome Comment Files
03/13/2015 PASS HMSL10052-101-1_LCMS.pdf
02/22/2011 PASS None