AZ-628 - Small Molecule (ID:10050-101)

HMS LINCS ID: 10050-101
Name: AZ-628
Alternative Names:
LINCS ID: LSM-1050
PubChem CID: 11676786
ChEBI ID:
ChEMBL ID:
Molecular Mass: 451.20
InChi: InChI=1S/C27H25N5O2/c1-17-8-9-21(31-25(33)18-6-5-7-19(12-18)27(2,3)15-28)14-24(17)30-20-10-11-23-22(13-20)26(34)32(4)16-29-23/h5-14,16,30H,1-4H3,(H,31,33)
InChi Key: ZGBGPEDJXCYQPH-UHFFFAOYSA-N
SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
BRAF, CIT, CSF1R, DDR1, EPHA4, EPHA6, EPHB2, EPHB3, MAPK11, MAPK14, PDGFRA, PDGFRB, RAF1, STK10, YES1
10
(confirmed non-binding)
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Batch Information for HMSL10050-101-2:

HMS LINCS Batch ID: 10050-101-2
Provider: AstraZeneca
Provider Batch ID:
Salt: 101
Molecular Formula:
Molecular Weight:
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-12-02