AC220 - Small Molecule (ID:10037-101)

HMS LINCS ID: 10037-101
Name: AC220
Alternative Names:
LINCS ID: LSM-1037
PubChem CID: 24889392
ChEBI ID:
ChEMBL ID:
Molecular Mass: 560.22
InChi: InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)
InChi Key: CVWXJKQAOSCOAB-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
CSF1R, DDR1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB, RET
2
(equivalent to 100 nM ≤ Kd < 1µM)
DDR2, HIPK4, MAP4K5, MAPK15, MYLK3, NTRK2, NTRK3, RIPK1, TKT
3
(equivalent to 1µM ≤ Kd < 10 µM)
ABL1, EPHA3, EPHA6, EPHA7, EPHB6, FRK, LCK, LYN, MAP3K19, MAP3K7, MAP4K4, MKNK2, MUSK, NTRK1, RIPK2, SLK, STK10, TIE1, TNIK
10
(confirmed non-binding)
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Batch Information for HMSL10037-101-1:

HMS LINCS Batch ID: 10037-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HY-13001-20101013
Salt: 101
Molecular Formula: C29H32N6O4S
Molecular Weight: 560.67
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10037-101-1:

Date HMS QC Outcome Comment Files
06/06/2011 PASS None