Saracatinib - Small Molecule (ID:10032-101)

HMS LINCS ID: 10032-101
Name: Saracatinib
Alternative Names: AZD0530
LINCS ID: LSM-1032
PubChem CID: 10302451
ChEBI ID:
ChEMBL ID: 217092
Molecular Mass: 541.21
InChi: InChI=1S/C27H32ClN5O5/c1-32-6-8-33(9-7-32)10-13-35-19-14-21-24(23(15-19)38-18-4-11-34-12-5-18)27(30-16-29-21)31-25-20(28)2-3-22-26(25)37-17-36-22/h2-3,14-16,18H,4-13,17H2,1H3,(H,29,30,31)
InChi Key: OUKYUETWWIPKQR-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
ABL1, LCK, SRC, YES1
2
(equivalent to 100 nM ≤ Kd < 1µM)
CSK, KIT
3
(equivalent to 1µM ≤ Kd < 10 µM)
EGFR, PDGFRB
10
(confirmed non-binding)
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Batch Information for HMSL10032-101-2:

HMS LINCS Batch ID: 10032-101-2
Provider: Haoyuan chemexpress
Provider Batch ID:
Salt: 101
Molecular Formula: C27H32ClN5O5
Molecular Weight: 542.03
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-12-02