AT-7519 - Small Molecule (ID:10004-102)
| HMS LINCS ID: |
10004-102
|
| Name: | AT-7519 |
| Alternative Names: | |
| LINCS ID: | LSM-1004 |
| PubChem CID: | 11338033 |
| ChEBI ID: | |
| ChEMBL ID: | 445813 |
| Molecular Mass: | 381.08 |
| InChi: | InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24) |
| InChi Key: | OVPNQJVDAFNBDN-UHFFFAOYSA-N |
| SMILES: | C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
CASK, CCNA1, CCNA2, CDK11A, CDK11B, CDK13, CDK14, CDK15, CDK16, CDK17, CDK18, CDK2, CDK3, CDK4, CDK7, CDK9, CDKL5, CDKN3, GSK3A, GSK3B, ICK, MAK, MAPK7, TAOK2, TAOK3 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | CCNB1, CCNB2, CCNB3, CCND1, CCND3, CDK1, CDK5, CDK6, CLK1, CLK3, DYRK1A, DYRK1B, MAPK15, TAOK1 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | CAMKK2, CDK19, CDKL2, CLK2, CLK4, DCLK2, DCLK3, DMPK, DYRK2, SLK, TLK1 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10004-102-2 | Haoyuan chemexpress | HY-50943-20120605 |
(Kd <100 nM)