Seliciclib - Small Molecule (ID:10001-101)

HMS LINCS ID: 10001-101
Name: Seliciclib
Alternative Names: (R)-Roscovitine; CYC202
LINCS ID: LSM-1001
PubChem CID: 160355
ChEBI ID:
ChEMBL ID: 14762
Molecular Mass: 354.22
InChi: InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1
InChi Key: BTIHMVBBUGXLCJ-OAHLLOKOSA-N
SMILES: CC[C@H](CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-07-12

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
CCNA1, CCNA2, CCNB1, CCNB2, CCNB3, CCNE1, CCNE2, CCNH, CCNT1, CDK1, CDK2, CDK5, CDK5R1, CDK7, CDK9, CLK2, CSNK1E
3
(equivalent to 1µM ≤ Kd < 10 µM)
ALK, CDK16, Clk1, CLK1, CLK4, CSNK1D, CSNK1G3, DYRK1A, DYRK1B, PAK4, TTK
10
(confirmed non-binding)
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Batch Information for HMSL10001-101-1:

HMS LINCS Batch ID: 10001-101-1
Provider: Haoyuan chemexpress
Provider Batch ID: HM-001_TM-20090805
Salt: 101
Molecular Formula: C19H26N6O
Molecular Weight: 354.45
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10001-101-1:

Date HMS QC Outcome Comment Files
03/13/2015 PASS HMSL10001-101-1_LCMS.pdf
02/22/2011 PASS None