Proteins
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| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 201102 | PLK1 | 201102 | P53350 | Serine/threonine-protein kinase PLK1; polo-like kinase 1 (Drosophila); PLK; PLK1; STPK13 | KiNativ | ||||
| 201103 | PIK3CA | 201103 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | |||||
| 201104 | PIK3CB | 201104 | P42338 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; DKFZp779K1237; MGC133043; P110BETA; PI3K; PI3KBETA; PIK3C1; PIK3CB; PI3K-beta | |||||
| 201105 | PIK3CD | 201105 | O00329 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; p110D; P110DELTA; PI3K; PIK3CD; PI3K-delta | |||||
| 201106 | PIK3CG | 201106 | P48736 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; PI3CG; PI3K; PI3Kgamma; PIK3; PIK3CG | |||||
| 201107 | MAP3K14 | 201107 | Q99558 | Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; NIK | KINOMEscan | ||||
| 201108 | SGK2 | 201108 | Q9HBY8 | Serine/threonine-protein kinase Sgk2; Serum/glucocorticoid-regulated kinase 2 | KINOMEscan | ||||
| 201109 | ABL1 | 201109 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | |||||
| 201110 | ACVR1 | 201110 | Q04771 | Activin A receptor, type I; ACTRI; ACVR1; ACVR1A; ACVRLK2; ALK2; FOP; SKR1; TSRI | |||||
| 201111 | BRD2 | 201111 | P25440 | Bromodomain-containing protein 2; KIAA9001; RING3 | |||||
| 201112 | BRD4 | 201112 | O60885 | Bromodomain-containing protein 4; HUNK1 | |||||
| 201113 | CDC7 | 201113 | O00311 | Cell division cycle 7-related protein kinase; CDC7L1 | |||||
| 201114 | CENPE | 201114 | Q02224 | Centromere-associated protein E | |||||
| 201115 | CP2C9 | 201115 | P11712 | Cytochrome P450 2C9 | |||||
| 201116 | DCOR | 201116 | P11926 | Ornithine decarboxylase | |||||
| 201117 | DNMT1 | 201117 | P26358 | DNA (cytosine-5)-methyltransferase 1 | |||||
| 201118 | DYR | 201118 | P26358 | Dihydrofolate reductase | |||||
| 201119 | EGLN1 | 201119 | Q9GZT9 | Egl nine homolog 1 | |||||
| 201120 | EHMT2 | 201120 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | |||||
| 201121 | ELK3 | 201121 | P41970 | ETS domain-containing protein Elk-3 | |||||
| 201122 | EP300 | 201122 | Q09472 | Histone acetyltransferase p300 | |||||
| 201123 | ESR1 | 201123 | P03372 | Estrogen receptor | |||||
| 201124 | FDFT | 201124 | P37268 | Squalene synthase | |||||
| 201125 | HDAC1 | 201125 | Q13547 | Histone deacetylase 1 | |||||
| 201126 | HDAC4 | 201126 | P56524 | Histone deacetylase 4 | |||||
| 201127 | HDAC6 | 201127 | Q9UBN7 | Histone deacetylase 6 | |||||
| 201128 | KDM1A | 201128 | O60341 | Lysine-specific histone demethylase 1A | |||||
| 201129 | KDM2A | 201129 | Q9Y2K7 | Lysine-specific demethylase 2A | |||||
| 201130 | KDM4A | 201130 | O75164 | Lysine-specific demethylase 4A | |||||
| 201131 | KDM6B | 201131 | O15054 | Lysine-specific demethylase 6B | |||||
| 201132 | KIF11 | 201132 | P52732 | Kinesin-like protein KIF11 | |||||
| 201133 | KPCB | 201133 | P05771 | Protein kinase C beta type | |||||
| 201134 | LMBL1 | 201134 | Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | |||||
| 201135 | LMBL3 | 201135 | Q96JM7 | Lethal(3)malignant brain tumor-like protein 3 | |||||
| 201136 | M3K8 | 201136 | P41279 | Mitogen-activated protein kinase kinase kinase 8 | |||||
| 201137 | MELK | 201137 | Q14680 | Maternal embryonic leucine zipper kinase; HPK38; KIAA0175 | |||||
| 201138 | MMP2 | 201138 | P08253 | 72 kDa type IV collagenase | |||||
| 201139 | Cdc25C | 201139 | P30307 | M-phase inducer phosphatase 3; Dual specificity phosphatase Cdc25C | |||||
| 201140 | PAK4 | 201140 | O96013 | P21 protein (Cdc42/Rac)-activated kinase 4; PAK4 | |||||
| 201141 | PARP-1 | 201141 | P09874 | Poly [ADP-ribose] polymerase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1 | |||||
| 201142 | PGH1 | 201142 | P23219 | Prostaglandin G/H synthase 1 | |||||
| 201143 | PIM1 | 201143 | P11309 | Pim-1 oncogene; PIM; PIM1 | |||||
| 201144 | PP1A | 201144 | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | |||||
| 201145 | PSB5 | 201145 | P28074 | Proteasome subunit beta type-5 | |||||
| 201146 | RIR1 | 201146 | P23921 | Ribonucleoside-diphosphate reductase large subunit | |||||
| 201147 | ROCK1 | 201147 | Q13464 | Rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; MGC131603; MGC43611; P160ROCK; PRO0435; ROCK1 | |||||
| 201148 | RPA1 | 201148 | O95602 | DNA-directed RNA polymerase I subunit RPA1 | |||||
| 201149 | SIK1 | 201149 | P57059 | Serine/threonine-protein kinase SIK1; salt-inducible kinase 1; MSK; SIK; SIK1; SNF1LK | |||||
| 201150 | SIR1 | 201150 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1; hSIRT1; regulatory protein SIR2 homolog 1 | |||||
| 201151 | SIR2 | 201151 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2; regulatory protein SIR2 homolog 2 |