Proteins
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200501 | c-Kit | 200501 | P10721 | Mast/stem cell growth factor receptor Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | |||||
200502 | c-Met | 200502 | P08581 | Hepatocyte growth factor receptor; met proto-oncogene (hepatocyte growth factor receptor) | |||||
200503 | c-Raf | 200503 | P04049 | RAF proto-oncogene serine/threonine-protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1 | |||||
200504 | CSF1R | 200504 | P07333 | Macrophage colony-stimulating factor 1 receptor; colony stimulating factor 1 receptor | |||||
200505 | DDR1 | 200505 | Q08345 | Epithelial discoidin domain-containing receptor 1; discoidin domain receptor tyrosine kinase 1 | |||||
200506 | DNA-PK | 200506 | P78527 | DNA-dependent protein kinase catalytic subunit | |||||
200507 | EGFR | 200507 | P00533 | Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | |||||
200508 | EPHB3 | 200508 | P54753 | Ephrin type-B receptor 3; EPHB3; ETK2; HEK2; TYRO6 | |||||
200509 | erbB-2 | 200509 | P04626 | Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340 | |||||
200510 | ERK-1 | 200510 | P27361 | Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1 | |||||
200511 | ERK-2 | 200511 | P28482 | Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2 | |||||
200512 | ERK5 | 200512 | Q13164 | Mitogen-activated protein kinase 7 | |||||
200513 | FAK | 200513 | Q05397 | Focal adhesion kinase 1; PTK2 protein tyrosine kinase 2 | |||||
200514 | FGFR1 | 200514 | P11362 | Fibroblast growth factor receptor 1 | |||||
200515 | FLT3 | 200515 | P36888 | Receptor-type tyrosine-protein kinase FLT3; fms-related tyrosine kinase 3 | |||||
200516 | GSK-3 alpha | 200516 | P49840 | Glycogen synthase kinase-3 alpha; Serine/threonine-protein kinase GSK3A | |||||
200517 | GSK-3 beta | 200517 | P49841 | Glycogen synthase kinase-3 beta; Serine/threonine-protein kinase GSK3B | |||||
200518 | HSP90 | 200518 | |||||||
200519 | IGF1R | 200519 | P08069 | Insulin-like growth factor 1 receptor | |||||
200520 | IKKA | 200520 | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | |||||
200521 | IKKB | 200521 | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | |||||
200522 | IKKE | 200522 | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | |||||
200523 | JAK1 | 200523 | P23458 | Tyrosine-protein kinase JAK1; Janus kinase 1 | |||||
200524 | JAK2 | 200524 | O60674 | Tyrosine-protein kinase JAK2; Janus kinase 2 | |||||
200525 | JAK3 | 200525 | P52333 | Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; L-JAK | |||||
200526 | JNK1 | 200526 | P45983 | Mitogen-activated protein kinase 8 | |||||
200527 | MK09 | 200527 | P45984 | Mitogen-activated protein kinase 9; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-55; MAPK9; p54a; p54aSAPK; PRKM9; SAPK | |||||
200528 | JNK3 | 200528 | P53779 | Mitogen-activated protein kinase 10 | |||||
200529 | MDM2 | 200529 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | |||||
200530 | MP2K1 | 200530 | Q02750 | Dual specificity mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; MAP2K1; MAPKK1; MEK1; MEK1/MAP2K1; MKK1; PRKMK1 | |||||
200531 | MP2K2 | 200531 | P36507 | Dual specificity mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; FLJ26075; MAP2K2; MAPKK2; MEK2; MEK2/MAP2K2; MKK2; PRKMK2 | |||||
200532 | MP2K5 | 200532 | Q13163 | Dual specificity mitogen-activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; HsT17454; MAP2K5; MAPKK5; MEK5; PRKMK5 | |||||
200533 | M3K2 | 200533 | Q9Y2U5 | Mitogen-activated protein kinase kinase kinase 2; MAP3K2; MEKK2; MEKK2/MAP3K2; MEKK2B | |||||
200534 | MEKK3 | 200534 | Q99759 | Mitogen-activated protein kinase kinase kinase 3 | |||||
200535 | MNK1 | 200535 | Q9BUB5 | MAP kinase-interacting serine/threonine-protein kinase 1 | |||||
200536 | MNK2 | 200536 | Q9HBH9 | MAP kinase-interacting serine/threonine-protein kinase 2 | |||||
200537 | mTOR | 200537 | P42345 | Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1 | |||||
200538 | NF-kB | 200538 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells | ||||||
200539 | MK14 | 200539 | Q16539 | Mitogen-activated protein kinase 14; CSBP1; CSBP2; CSPB1; EXIP; MAPK14; Mxi2; p38; p38a; p38ALPHA; p38-alpha; PRKM14; PRKM15; RK; SAPK2A | |||||
200540 | MK11 | 200540 | Q15759 | Mitogen-activated protein kinase 11; MAPK11; p38-2; p38b; p38Beta; p38-beta; P38BETA2; PRKM11; SAPK2; SAPK2B | |||||
200541 | MK13 | 200541 | O15264 | Mitogen-activated protein kinase 13; MAPK13; MGC99536; p38d; p38delta; p38-delta; PRKM13; SAPK4 | |||||
200542 | MK12 | 200542 | P53778 | Mitogen-activated protein kinase 12; ERK3; ERK6; MAPK12; p38g; P38GAMMA; p38-gamma; PRKM12; SAPK3; SAPK-3 | |||||
200543 | p53 | 200543 | P04637 | Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53 | |||||
200544 | KS6B1 | 200544 | P23443 | Ribosomal protein S6 kinase 1 (EC 2.7.1.37) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) | |||||
200545 | P90RSK | 200545 | Ribosomal protein S6 kinase, 90kDa | ||||||
200546 | PARP | 200546 | Poly (ADP-ribose) polymerase family | ||||||
200547 | PDK1 | 200547 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | |||||
200548 | PI3K | 200548 | Phosphoinositide-3-kinase, catalytic | ||||||
200549 | PKC | 200549 | Protein kinase C | ||||||
200550 | PLC | 200550 |