Proteins

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200501 c-Kit 200501 P10721
Mast/stem cell growth factor receptor Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
200502 c-Met 200502 P08581
Hepatocyte growth factor receptor; met proto-oncogene (hepatocyte growth factor receptor)
200503 c-Raf 200503 P04049
RAF proto-oncogene serine/threonine-protein kinase; v-raf-1 murine leukemia viral oncogene homolog 1
200504 CSF1R 200504 P07333
Macrophage colony-stimulating factor 1 receptor; colony stimulating factor 1 receptor
200505 DDR1 200505 Q08345
Epithelial discoidin domain-containing receptor 1; discoidin domain receptor tyrosine kinase 1
200506 DNA-PK 200506 P78527
DNA-dependent protein kinase catalytic subunit
200507 EGFR 200507 P00533
Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
200508 EPHB3 200508 P54753
Ephrin type-B receptor 3; EPHB3; ETK2; HEK2; TYRO6
200509 erbB-2 200509 P04626
Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340
200510 ERK-1 200510 P27361
Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1
200511 ERK-2 200511 P28482
Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2
200512 ERK5 200512 Q13164
Mitogen-activated protein kinase 7
200513 FAK 200513 Q05397
Focal adhesion kinase 1; PTK2 protein tyrosine kinase 2
200514 FGFR1 200514 P11362
Fibroblast growth factor receptor 1
200515 FLT3 200515 P36888
Receptor-type tyrosine-protein kinase FLT3; fms-related tyrosine kinase 3
200516 GSK-3 alpha 200516 P49840
Glycogen synthase kinase-3 alpha; Serine/threonine-protein kinase GSK3A
200517 GSK-3 beta 200517 P49841
Glycogen synthase kinase-3 beta; Serine/threonine-protein kinase GSK3B
200518 HSP90 200518
200519 IGF1R 200519 P08069
Insulin-like growth factor 1 receptor
200520 IKKA 200520 O15111
Inhibitor of nuclear factor kappa-B kinase subunit alpha
200521 IKKB 200521 O14920
Inhibitor of nuclear factor kappa-B kinase subunit beta
200522 IKKE 200522 Q14164
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
200523 JAK1 200523 P23458
Tyrosine-protein kinase JAK1; Janus kinase 1
200524 JAK2 200524 O60674
Tyrosine-protein kinase JAK2; Janus kinase 2
200525 JAK3 200525 P52333
Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; L-JAK
200526 JNK1 200526 P45983
Mitogen-activated protein kinase 8
200527 MK09 200527 P45984
Mitogen-activated protein kinase 9; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-55; MAPK9; p54a; p54aSAPK; PRKM9; SAPK
200528 JNK3 200528 P53779
Mitogen-activated protein kinase 10
200529 MDM2 200529 Q00987
E3 ubiquitin-protein ligase Mdm2
200530 MP2K1 200530 Q02750
Dual specificity mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; MAP2K1; MAPKK1; MEK1; MEK1/MAP2K1; MKK1; PRKMK1
200531 MP2K2 200531 P36507
Dual specificity mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; FLJ26075; MAP2K2; MAPKK2; MEK2; MEK2/MAP2K2; MKK2; PRKMK2
200532 MP2K5 200532 Q13163
Dual specificity mitogen-activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; HsT17454; MAP2K5; MAPKK5; MEK5; PRKMK5
200533 M3K2 200533 Q9Y2U5
Mitogen-activated protein kinase kinase kinase 2; MAP3K2; MEKK2; MEKK2/MAP3K2; MEKK2B
200534 MEKK3 200534 Q99759
Mitogen-activated protein kinase kinase kinase 3
200535 MNK1 200535 Q9BUB5
MAP kinase-interacting serine/threonine-protein kinase 1
200536 MNK2 200536 Q9HBH9
MAP kinase-interacting serine/threonine-protein kinase 2
200537 mTOR 200537 P42345
Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
200538 NF-kB 200538
Nuclear factor of kappa light polypeptide gene enhancer in B-cells
200539 MK14 200539 Q16539
Mitogen-activated protein kinase 14; CSBP1; CSBP2; CSPB1; EXIP; MAPK14; Mxi2; p38; p38a; p38ALPHA; p38-alpha; PRKM14; PRKM15; RK; SAPK2A
200540 MK11 200540 Q15759
Mitogen-activated protein kinase 11; MAPK11; p38-2; p38b; p38Beta; p38-beta; P38BETA2; PRKM11; SAPK2; SAPK2B
200541 MK13 200541 O15264
Mitogen-activated protein kinase 13; MAPK13; MGC99536; p38d; p38delta; p38-delta; PRKM13; SAPK4
200542 MK12 200542 P53778
Mitogen-activated protein kinase 12; ERK3; ERK6; MAPK12; p38g; P38GAMMA; p38-gamma; PRKM12; SAPK3; SAPK-3
200543 p53 200543 P04637
Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
200544 KS6B1 200544 P23443
Ribosomal protein S6 kinase 1 (EC 2.7.1.37) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha)
200545 P90RSK 200545
Ribosomal protein S6 kinase, 90kDa
200546 PARP 200546
Poly (ADP-ribose) polymerase family
200547 PDK1 200547 O15530
3-phosphoinositide-dependent protein kinase 1
200548 PI3K 200548
Phosphoinositide-3-kinase, catalytic
200549 PKC 200549
Protein kinase C
200550 PLC 200550