Proteins
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
201293 | Visfatin | 201293 | P43490 | Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt); Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; PBEF: Visfatin | PeproTech | ||||
201294 | H3 (pS10) | 201294 | P68431 | pS10 | |||||
201295 | p21 | 201295 | P38936 | Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6 | |||||
201296 | KI-67 | 201296 | P46013 | Antigen KI-67 | |||||
201297 | Rb (pS807; pS811) | 201297 | P06400 | pS807; pS811 | |||||
201298 | S6 (pS235; pS236) | 201298 | P62753 | pS235; pS236 | |||||
201299 | S6 (pS240; pS244) | 201299 | P62753 | pS240; pS244 | |||||
201300 | Ep-CAM | 201300 | P16422 | Epithelial cell adhesion molecule; Ep-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; CD326 | |||||
201301 | Lamin-A/C | 201301 | P02545 | Prelamin-A/C; Lamin-A/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32 | |||||
201302 | PCNA | 201302 | P12004 | Proliferating cell nuclear antigen; Cyclin | |||||
201303 | ERK-1 (pT202; pY204) | 201303 | P27361 | pT202; pY204 | |||||
201304 | ERK-2 (pT185; pY187) | 201304 | P28482 | pT185; pY187 | |||||
201305 | K4 | 201305 | P19013 | Keratin, type II cytoskeletal 4; Cytokeratin-4; CK-4; Keratin-4; Type-II keratin Kb4 | |||||
201306 | K5 | 201306 | P13647 | Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; Type-II keratin Kb5 | |||||
201307 | K6A | 201307 | P02538 | Keratin, type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Cytokeratin-6D; CK-6D; Keratin-6A; Type-II keratin Kb6; Hom s 5 | |||||
201308 | K6B | 201308 | P04259 | Keratin, type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; Type-II keratin Kb10 | |||||
201309 | K6C | 201309 | P48668 | Keratin, type II cytoskeletal 6C; Cytokeratin-6C; CK-6C; Cytokeratin-6E; CK-6E; Keratin K6h; Keratin-6C; Type-II keratin Kb12 | |||||
201310 | K8 | 201310 | P05787 | Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Type-II keratin Kb8 | |||||
201311 | K10 | 201311 | P13645 | Keratin, type I cytoskeletal 10; Cytokeratin-10; CK-10 | |||||
201312 | K13 | 201312 | P13646 | Keratin, type I cytoskeletal 13; Cytokeratin-13; CK-13 | |||||
201313 | K18 | 201313 | P05783 | Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18 | |||||
201314 | H2A.X (pS139) | 201314 | P16104 | pS139 | |||||
201315 | SOX-2 | 201315 | P48431 | Transcription factor SOX-2 | |||||
201316 | Beta-actin | 201316 | P60709 | Actin, cytoplasmic 1 | |||||
201317 | Tubulin beta chain | 201317 | P07437 | Tubulin beta-5 chain | |||||
201318 | c-Jun (pS73) | 201318 | P05412 | pS73 | |||||
201319 | c-Jun | 201319 | P05412 | Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 | |||||
201320 | TNF-a | 201320 | P01375 | Tumor Necrosis Factor-α; TNF-alpha; Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin | |||||
201321 | TNF10 | 201321 | P50591 | Tumor necrosis factor ligand superfamily member 10; TRAIL; Apo-2L | Sigma | Recombinant human TRAIL is a 168 amino acid polypeptide (19.6 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL/Apo2L protein,1 expressed in E. coli. 1. Wiley, S.R. et al., Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity, 3, 673-682 (1995). [source: Sigma Aldrich] | |||
201322 | rabbit gamma immunoglobin heavy and light chains | 201322 | rabbit IgG(H+L)
| ||||||
201323 | mouse gamma immunoglobin heavy and light chains | 201323 | mouse IgG(H+L)
| ||||||
201324 | CAMK1B | 201324 | Q6P2M8 | Calcium/calmodulin-dependent protein kinase type 1B; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase; CaM kinase I beta | KINOMEscan | ||||
201325 | FLT3(D835V) | 201325 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835V | |||
201326 | FLT3(ITD,D835V) | 201326 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD,D835V | |||
201327 | FLT3(ITD,F691L) | 201327 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD,F691L | |||
201328 | BARK1 | 201328 | P25098 | Beta-adrenergic receptor kinase 1; GRK2 | KINOMEscan | ||||
201329 | BARK2 | 201329 | P35626 | Beta-adrenergic receptor kinase 2; GRK3 | KINOMEscan | ||||
201330 | FYV1 | 201330 | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase; PIKfyve | KINOMEscan | ||||
201331 | TSSK3 | 201331 | Q96PN8 | Testis-specific serine/threonine-protein kinase 3; TSK-3 | KINOMEscan | ||||
201332 | PIK3C3 | 201332 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3; PI3-kinase type 3; VPS34 | KINOMEscan | ||||
201333 | WNK2 | 201333 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | KINOMEscan | ||||
201334 | WNK4 | 201334 | Q96J92 | Serine/threonine-protein kinase WNK4 | KINOMEscan | ||||
201335 | Rb (pS807) | 201335 | P06400 | pS807 | |||||
201336 | Rb (pS811) | 201336 | P06400 | pS811 | |||||
201337 | ERK-1 (pT202) | 201337 | P27361 | pT202 | |||||
201338 | ERK-2 (pT185) | 201338 | P28482 | pT185 | |||||
201339 | Aurora kinase A (pT288) | 201339 | O14965 | pT288 | |||||
201340 | Aurora kinase B (pT232) | 201340 | Q96GD4 | pT232 | |||||
201341 | Aurora kinase C (pT198) | 201341 | Q9UQB9 | pT198 | |||||
201342 | S6 | 201342 | P62753 | 40S ribosomal protein S6, Phosphoprotein NP33 | |||||
201343 | PARP-1 (D214-cleaved) | 201343 | P09874 | D214-cleaved | |||||
201344 | p27Kip1 | 201344 | P46527 | Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27 | |||||
201345 | AKT1 (mouse) | 201345 | P31750 | RAC-alpha serine/threonine-protein kinase; AKT1 kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; Thymoma viral proto-oncogene | |||||
201346 | AKT2 (mouse) | 201346 | Q60823 | RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta | |||||
201347 | AKT3 (mouse) | 201347 | Q9WUA6 | RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma | |||||
201348 | Vimentin | 201348 | P08670 | ||||||
201349 | NF-kB p65 | 201349 | Q04206 | Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 | |||||
201350 | FOXO3a | 201350 | O43524 | Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 | |||||
201351 | Cyclin-D1 | 201351 | P24385 | G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene | |||||
201352 | BAX | 201352 | Q07812 | Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4 | |||||
201353 | E-cadherin | 201353 | P12830 | CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324 | |||||
201354 | H3 | 201354 | P68431 | Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l | |||||
201355 | Rb | 201355 | P06400 | Retinoblastoma-associated protein; p105-Rb; pRb; pp110 | |||||
201356 | H2A.X | 201356 | P16104 | Histone H2AX; H2a/x; Histone H2A.X | |||||
201357 | EGF | 201357 | P01133 | Epidermal Growth Factor; Urogastrone; URG | PeproTech | ||||
201358 | Cdc25A | 201358 | P30304 | M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A | |||||
201359 | Cyclin-D2 | 201359 | P30279 | G1/S-specific cyclin-D2 | |||||
201360 | Cyclin-D3 | 201360 | P30281 | G1/S-specific cyclin-D3 | |||||
201361 | Cyclin-E1 | 201361 | P24864 | G1/S-specific cyclin-E1 | |||||
201362 | p27Kip1 (pT187) | 201362 | P46527 | pT187 | |||||
201363 | Cyclin-A1 | 201363 | P78396 | ||||||
201364 | Cyclin-A2 | 201364 | P20248 | Cyclin-A | |||||
201365 | p27Kip1 (mouse) | 201365 | P46414 | Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27 | |||||
201366 | CDK2 (pT160) | 201366 | P24941 | pT160 | |||||
201367 | GSK-3 alpha (pS21) | 201367 | P49840 | pS21 | |||||
201368 | GSK-3 beta (pS9) | 201368 | P49841 | pS9 | |||||
201369 | mTOR (pS2448) | 201369 | P42345 | pS2448 | |||||
201370 | Myt1 | 201370 | Q99640 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Myt1 kinase | |||||
201371 | Myt1 (pS83) | 201371 | Q99640 | pS83 | |||||
201372 | S6K-alpha-1 | 201372 | Q15418 | Ribosomal protein S6 kinase alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; Ribosomal S6 kinase 1; RSK-1 | |||||
201373 | S6K-alpha-1 (pT359) | 201373 | Q15418 | pT359 | |||||
201374 | S6K-alpha-2 | 201374 | Q15349 | Ribosomal protein S6 kinase alpha-2; 90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ribosomal S6 kinase 3; RSK-3; pp90RSK3 | |||||
201375 | S6K-alpha-2 (pT365) | 201375 | Q15349 | pT365 | |||||
201376 | S6K-alpha-3 (pT356) | 201376 | P51812 | pT356 | |||||
201377 | S6K-alpha-1 (pT573) | 201377 | Q15418 | pT573 | |||||
201378 | Tuberin | 201378 | P49815 | Tuberous sclerosis 2 protein | |||||
201379 | Tuberin (pS1387) | 201379 | P49815 | pS1387 | |||||
201380 | WEE1hu (pS642) | 201380 | P30291 | pS642 | |||||
201381 | S6K-alpha-1 (pS380) | 201381 | Q15418 | pS380 | |||||
201382 | S6K-alpha-2 (pS377) | 201382 | Q15349 | pS377 | |||||
201383 | S6K-alpha-3 (pS386) | 201383 | P51812 | pS386 | |||||
201384 | Cyclin-B1 | 201384 | P14635 | G2/mitotic-specific cyclin-B1 | |||||
201385 | FoxM1 | 201385 | Q08050 | Forkhead box protein M1; Forkhead-related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HNF-3/fork-head homolog 11; M-phase phosphoprotein 2; MPM-2 reactive phosphoprotein 2; Transcription factor Trident; Winged-helix factor from INS-1 cells | |||||
201386 | CDK1 (pY15) | 201386 | P06493 | pY15 | |||||
201387 | CDK2 (pY15) | 201387 | P24941 | pY15 | |||||
201388 | p27Kip1 (pS10) | 201388 | P46527 | pS10 | |||||
201389 | p57Kip2 | 201389 | P49918 | Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57 | |||||
201390 | Akt-1 (pS473) | 201390 | P31749 | pS473 | |||||
201391 | p57Kip2 (pT310) | 201391 | P49918 | pT310 | |||||
201392 | Survivin | 201392 | O15392 | Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin | |||||
201393 | 4E-BP1 (mouse) | 201393 | Q60876 | Eukaryotic translation initiation factor 4E-binding protein 1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I | |||||
201394 | 4E-BP1 (pT36; pT45) (mouse) | 201394 | Q60876 | pT36; pT45 | |||||
201395 | 4E-BP1 | 201395 | Q13541 | Eukaryotic translation initiation factor 4E-binding protein 1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I | |||||
201396 | 4EBP1 (pT37; pT46) | 201396 | Q13541 | pT37; pT46 | |||||
201397 | 4EBP1 (pT37) | 201397 | Q13541 | pT37 | |||||
201398 | 4EBP1 (pT46) | 201398 | Q13541 | pT46 | |||||
201399 | NGFR | 201399 | P08138 | Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD271 | |||||
201400 | EGF | 201400 | P01133 | Epidermal Growth Factor; Urogastrone; URG | PeproTech | ||||
201401 | IGF-I | 201401 | P05019 | Insulin-like growth factor I; Mechano growth factor; MGF; Somatomedin-C | PeproTech | ||||
201402 | NRG1 | 201402 | Q02297 | Pro-neuregulin-1; Pro-NRG1; Neuregulin-1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-derived factor | PeproTech | ||||
201403 | HGF | 201403 | P14210 | Hepatocyte growth factor; Hepatopoietin-A; Scatter factor; SF | PeproTech | ||||
201404 | EPR | 201404 | O14944 | Proepiregulin; Epiregulin | PeproTech | ||||
201405 | BTC | 201405 | P35070 | Probetacellulin; Betacellulin | PeproTech | ||||
201406 | RP-A p32 | 201406 | P15927 | Replication protein A 32 kDa subunit; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34 | |||||
201407 | E2F-1 | 201407 | Q01094 | Transcription factor E2F1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1 | |||||
201408 | FOXO1a | 201408 | Q12778 | Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma | |||||
201409 | c-Myc | 201409 | P01106 | Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64 | |||||
201410 | CDK4 | 201410 | P11802 | Cyclin-dependent kinase 4; cell division protein kinase 4 | KINOMEscan | ||||
201411 | RPS6KA1(Kin.Dom.1-N-terminal) | 201411 | Q15418 | Ribosomal protein S6 kinase, 90kDa, polypeptide 1; HU-1; MAPKAPK1A; RPS6KA1; RSK; RSK1; RSK3 | KINOMEscan | Kin.Dom.1 | |||
201412 | RPS6KA1(Kin.Dom.2-C-terminal) | 201412 | Q15418 | Ribosomal protein S6 kinase, 90kDa, polypeptide 1; HU-1; MAPKAPK1A; RPS6KA1; RSK; RSK1; RSK3 | KINOMEscan | Kin.Dom.2 | |||
201413 | RPS6KA2(Kin.Dom.1-N-terminal) | 201413 | Q15349 | Ribosomal protein S6 kinase, 90kDa, polypeptide 2; HU-2; MAPKAPK1C; p90RSK; p90-RSK3; pp90RSK3; RPS6KA2; RSK; RSK1; RSK1/p90RSK; RSK3; S6K-alpha; S6K-alpha2 | KINOMEscan | Kin.Dom.1 | |||
201414 | RPS6KA2(Kin.Dom.2-C-terminal) | 201414 | Q15349 | Ribosomal protein S6 kinase, 90kDa, polypeptide 2; HU-2; MAPKAPK1C; p90RSK; p90-RSK3; pp90RSK3; RPS6KA2; RSK; RSK1; RSK1/p90RSK; RSK3; S6K-alpha; S6K-alpha2 | KINOMEscan | Kin.Dom.2 | |||
201415 | RPS6KA3(Kin.Dom.1-N-terminal) | 201415 | P51812 | Ribosomal protein S6 kinase, 90kDa, polypeptide 3; CLS; HU-3; ISPK-1; MAPKAPK1B; MRX19; p90-RSK2; pp90RSK2; RPS6KA3; RSK; RSK2; S6K-alpha3 | KINOMEscan | Kin.Dom.1 | |||
201416 | RPS6KA6(Kin.Dom.1-N-terminal) | 201416 | Q9UK32 | Ribosomal protein S6 kinase, 90kDa, polypeptide 6; PP90RSK4; RPS6KA6; RSK4 | KINOMEscan | Kin.Dom.1 | |||
201417 | RPS6KA6(Kin.Dom.2-C-terminal) | 201417 | Q9UK32 | Ribosomal protein S6 kinase, 90kDa, polypeptide 6; PP90RSK4; RPS6KA6; RSK4 | KINOMEscan | Kin.Dom.2 | |||
201418 | MISR2 | 201418 | Q16671 | Anti-Muellerian hormone type-2 receptor; AMH type II receptor; AMHR2 | KINOMEscan | ||||
201419 | PIK3CA(H1047R) | 201419 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047R |