Proteins
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| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200401 | RSK2(Kin.Dom.1-N-terminal) | 200401 | P51812 | Ribosomal protein S6 kinase alpha 3; KS6A3; S6K-alpha-3; p90-RSK 3; MAPKAPK-1b; pp90RSK2 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
| 200402 | RSK3(Kin.Dom.1-N-terminal) | 200402 | Q15349 | Ribosomal protein S6 kinase, 90kDa, polypeptide 2; HU-2; MAPKAPK1C; p90RSK; p90-RSK3; pp90RSK3; RPS6KA2; RSK; RSK1; RSK1/p90RSK; RSK3; S6K-alpha; S6K-alpha2 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
| 200403 | RSK3(Kin.Dom.2-C-terminal) | 200403 | Q15349 | Ribosomal protein S6 kinase, 90kDa, polypeptide 2; HU-2; MAPKAPK1C; p90-RSK3; pp90RSK3; RPS6KA2; RSK; RSK1; RSK1~b; RSK3; S6K-alpha; S6K-alpha2 | KINOMEscan | Kin.Dom.2-C-terminal) | Wild Type; Partial length | ||
| 200404 | RSK4(Kin.Dom.1-N-terminal) | 200404 | Q9UK32 | Ribosomal protein S6 kinase alpha 6; S6K-alpha-6; p90-RSK 6; pp90RSK4 | KINOMEscan | Kin.Dom.1-N-terminal) | Wild Type; Partial length | ||
| 200405 | RSK4(Kin.Dom.2-C-terminal) | 200405 | Q9UK32 | Ribosomal protein S6 kinase alpha 6; S6K-alpha-6; p90-RSK 6; pp90RSK4 | KINOMEscan | Kin.Dom.2-C-terminal) | Wild Type; Partial length | ||
| 200406 | S6K1 | 200406 | P23443 | Ribosomal protein S6 kinase, 70kDa, polypeptide 1; p70(S6K)-alpha; p70-alpha; p70S6K; p70-S6K; PS6K; RPS6KB1; S6K; S6K1; STK14A | KINOMEscan | Wild Type; Partial length | |||
| 200407 | SBK1 | 200407 | Q52WX2 | SH3-binding domain kinase 1; Sbk; SBK1 | KINOMEscan | Wild Type; Partial length | |||
| 200408 | SgK110 | 200408 | P0C264 | Putative uncharacterized serine/threonine-protein kinase (Sugen kinase 110); SgK110 | KINOMEscan | Wild Type; Partial length | |||
| 200409 | SGK3 | 200409 | Q96BR1 | Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid-regulated kinase 3; CISK; DKFZp781N0293; SGKL | KINOMEscan | Wild Type; Partial length | |||
| 200410 | SIK1 | 200410 | P57059 | Serine/threonine-protein kinase SIK1; salt-inducible kinase 1; MSK; SIK; SIK1; SNF1LK | KINOMEscan | Wild Type; Partial length | |||
| 200411 | SIK2 | 200411 | Q9H0K1 | Serine/threonine-protein kinase SIK2; salt-inducible kinase 2; DKFZp434K1115; KIAA0781; LOH11CR1I; QIK; SIK2; SNF1LK2 | KINOMEscan | Wild Type; Full length | |||
| 200412 | SLK | 200412 | Q9H2G2 | STE20-like serine/threonine-protein kinase; CTCL tumor antigen se20-9; bA16H23.1; KIAA0204; LOSK; MGC133067; se20-9; SLK; STK2 | KINOMEscan | Wild Type; Partial length | |||
| 200413 | SNARK | 200413 | Q9H093 | NUAK family, SNF1-like kinase, 2; DKFZp434J037; DKFZp686F01113; FLJ90349; NUAK2; SNARK | KINOMEscan | Wild Type; Partial length | |||
| 200414 | SNRK | 200414 | Q9NRH2 | SNF-related serine/threonine-protein kinase; SNF1-related kinase; DKFZp779A1866; FLJ20224; HSNFRK; KIAA0096; SNRK | KINOMEscan | Wild Type; Partial length | |||
| 200415 | SRC | 200415 | P12931 | Proto-oncogene tyrosine-protein kinase Src; V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); ASV; c-SRC; p60-Src; SRC; SRC1 | KINOMEscan | Wild Type; Partial length | |||
| 200416 | SRMS | 200416 | Q9H3Y6 | Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; C20orf148; dJ697K14.1; SRM; SRMS | KINOMEscan | Wild Type; Partial length | |||
| 200417 | SRPK1 | 200417 | Q96SB4 | SRSF protein kinase 1; SFRS protein kinase 1; Serine/arginine-rich protein-specific kinase 1; SFRSK1 | KINOMEscan | Wild Type; Full length | |||
| 200418 | SRPK2 | 200418 | P78362 | SFRS protein kinase 2; FLJ36101; SFRSK2; SRPK2 | KINOMEscan | Wild Type; Full length | |||
| 200419 | SRPK3 | 200419 | Q9UPE1 | SFRS protein kinase 3; MGC102944; MSSK1; SRPK3; STK23 | KINOMEscan | Wild Type; Partial length | |||
| 200420 | STK16 | 200420 | O75716 | Serine/threonine kinase 16; FLJ39635; KRCT; MGC16211; MPSK; MPSK1; PKL12; STK16; TSF1 | KINOMEscan | Wild Type; Partial length | |||
| 200421 | STK33 | 200421 | Q9BYT3 | Serine/threonine kinase 33 | KINOMEscan | Wild Type; Full length | |||
| 200422 | STK35 | 200422 | Q8TDR2 | Serine/threonine kinase 35; CLIK1; STK35; STK35L1 | KINOMEscan | Wild Type; Partial length | |||
| 200423 | STK36 | 200423 | Q9NRP7 | Serine/threonine kinase 36, fused homolog (Drosophila); DKFZp434N0223; FU; Fused; KIAA1278; STK36 | KINOMEscan | Wild Type; Partial length | |||
| 200424 | STK39 | 200424 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase; serine threonine kinase 39 (STE20/SPS1 homolog, yeast); DCHT; DKFZp686K05124; PASK; SPAK; STLK3 | KINOMEscan | Wild Type; Partial length | |||
| 200425 | SYK | 200425 | P43405 | Tyrosine-protein kinase SYK; spleen tyrosine kinase; p72-Syk; DKFZp313N1010; FLJ25043; FLJ37489; SYK | KINOMEscan | Wild Type; Partial length | |||
| 200426 | TAK1 | 200426 | O43318 | Mitogen-activated protein kinase kinase kinase 7; MAP3K7; MEKK7; TAK1; TGF1a | KINOMEscan | Wild Type; Partial length | |||
| 200427 | TAOK1 | 200427 | Q7L7X3 | Serine/threonine-protein kinase TAO1; prostate-derived STE20-like kinase 2; hKFC-B; FLJ14314; KIAA1361; MAP3K16; MARKK; PSK2; TAO1; TAOK1 | KINOMEscan | Wild Type; Partial length | |||
| 200428 | TAOK2 | 200428 | Q9UL54 | Serine/threonine-protein kinase TAO2; prostate-derived sterile 20-like kinase 1; hKFC-C; KIAA0881; MAP3K17; PSK; PSK1; PSK1-BETA; TAO2; TAOK2 | KINOMEscan | Wild Type; Partial length | |||
| 200429 | TAOK3 | 200429 | Q9H2K8 | Serine/threonine-protein kinase TAO3; TAO kinase 3; DKFZp666H245; DPK; FLJ31808; JIK; MAP3K18; TAO3 | KINOMEscan | Wild Type; Partial length | |||
| 200430 | TBK1 | 200430 | Q9UHD2 | Serine/threonine-protein kinase TBK1; TANK-binding kinase 1; NF-kappa-B-activating kinase; FLJ11330; NAK; T2K; TBK1 | KINOMEscan | Wild Type; Full length | |||
| 200431 | TEC | 200431 | P42680 | Tyrosine-protein kinase Tec; MGC126760; MGC126762; PSCTK4; TEC | KINOMEscan | Wild Type; Partial length | |||
| 200432 | TESK1 | 200432 | Q15569 | Testis-specific kinase 1; TESK1 | KINOMEscan | Wild Type; Full length | |||
| 200433 | TGFBR1 | 200433 | P36897 | Transforming growth factor, beta receptor 1; AAT5; ACVRLK4; ALK5; ALK-5; LDS1A; LDS2A; SKR4; TGFBR1; TGFR-1 | KINOMEscan | Wild Type; Partial length | |||
| 200434 | TGFBR2 | 200434 | P37173 | Transforming growth factor, beta receptor II (70/80kDa); AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TGFbeta-RII; TGFBR2; TGFR-2 | KINOMEscan | Wild Type; Partial length | |||
| 200435 | TIE1 | 200435 | P35590 | Tyrosine-protein kinase receptor Tie-1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; JTK14; TIE; TIE1 | KINOMEscan | Wild Type; Partial length | |||
| 200436 | TIE2 | 200436 | Q02763 | Angiopoietin-1 receptor; TEK tyrosine kinase, endothelial; CD202B; TEK; TIE2; TIE-2; VMCM; VMCM1 | KINOMEscan | Wild Type; Partial length | |||
| 200437 | TLK1 | 200437 | Q9UKI8 | Serine/threonine-protein kinase tousled-like 1; tousled-like kinase 1; KIAA0137; PKU-beta; TLK1 | KINOMEscan | Wild Type; Partial length | |||
| 200438 | TLK2 | 200438 | Q86UE8 | Serine/threonine-protein kinase tousled-like 2; tousled-like kinase 2; MGC44450; PKU-ALPHA; TLK2 | KINOMEscan | Wild Type; Partial length | |||
| 200439 | TNIK | 200439 | Q9UKE5 | TRAF2 and NCK interacting kinase; TNIK; TNIK/ZC2; ZC2 | KINOMEscan | Wild Type; Partial length | |||
| 200440 | TNK1 | 200440 | Q13470 | Non-receptor tyrosine-protein kinase TNK1; MGC46193; TNK1 | KINOMEscan | Wild Type; Full length | |||
| 200441 | TNK2 | 200441 | Q07912 | Tyrosine kinase, non-receptor, 2; ACK; ACK1; FLJ44758; FLJ45547; p21cdc42Hs; TNK2 | KINOMEscan | Wild Type; Partial length | |||
| 200442 | TNNI3K | 200442 | Q59H18 | TNNI3 interacting kinase; CARK; HH498; MGC142099; MGC33828; TNNI3K | KINOMEscan | Wild Type; Full length | |||
| 200443 | TRKA | 200443 | P04629 | Neurotrophic tyrosine kinase, receptor, type 1; DKFZp781I14186; MTC; NTRK1; p140-TrkA; TRK; TRK1; TRKA; Trk-A | KINOMEscan | Wild Type; Partial length | |||
| 200444 | TRKB | 200444 | Q16620 | Neurotrophic tyrosine kinase, receptor, type 2; GP145-TrkB; NTRK2; TRKB | KINOMEscan | Wild Type; Partial length | |||
| 200445 | TRKC | 200445 | Q16288 | Neurotrophic tyrosine kinase, receptor, type 3; gp145(trkC); NTRK3; TRKC | KINOMEscan | Wild Type; Partial length | |||
| 200446 | TRPM6 | 200446 | Q9BX84 | Transient receptor potential cation channel, subfamily M, member 6; ChaK2; HMGX; HOMG; HOMG1; HSH; TRPM6 | KINOMEscan | Wild Type; Partial length | |||
| 200447 | TSSK1 | 200447 | Q9BXA7 | Testis-specific serine kinase 1B; FKSG81; SPOGA4; STK22D; TSSK1; TSSK1B | KINOMEscan | Wild Type; Full length | |||
| 200448 | TTK | 200448 | P33981 | TTK protein kinase; CT96; ESK; FLJ38280; MPS1; MPS1L1; PYT; TTK | KINOMEscan | Wild Type; Partial length | |||
| 200449 | TXK | 200449 | P42681 | TXK tyrosine kinase; BTKL; MGC22473; PSCTK5; PTK4; RLK; TKL; TXK | KINOMEscan | Wild Type; Partial length | |||
| 200450 | TYK2(JH1domain-catalytic) | 200450 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | JH1domain-catalytic | Wild Type; Partial length | ||
| 200451 | TYK2(JH2domain-pseudokinase) | 200451 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | JH2domain-pseudokinase | Wild Type; Partial length | ||
| 200452 | TYK2(Kin.Dom.1) | 200452 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | Kin.Dom.1 | |||
| 200453 | TYK2(Kin.Dom.2) | 200453 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KINOMEscan | Kin.Dom.2 | |||
| 200454 | TYRO3 | 200454 | Q06418 | TYRO3 protein tyrosine kinase; BYK; Dtk; FLJ16467; RSE; Sky; Tif; TYRO3; Tyro3/Sky | KINOMEscan | Wild Type; Partial length | |||
| 200455 | ULK1 | 200455 | O75385 | Serine/threonine-protein kinase ULK1; Unc-51-like kinase 1 (C. elegans); ATG1; FLJ38455; FLJ46475; ULK1; UNC51; Unc51.1 | KINOMEscan | Wild Type; Partial length | |||
| 200456 | ULK2 | 200456 | Q8IYT8 | Serine/threonine-protein kinase ULK2; Unc-51-like kinase 2 (C. elegans); KIAA0623; ULK2; Unc51.2 | KINOMEscan | Wild Type; Partial length | |||
| 200457 | ULK3 | 200457 | Q6PHR2 | Serine/threonine-protein kinase ULK3; Unc-51-like kinase 3 (C. elegans); DKFZp434C131; FLJ90566; ULK3 | KINOMEscan | Wild Type; Partial length | |||
| 200458 | VGFR2 | 200458 | P35968 | Vascular endothelial growth factor receptor 2; kinase insert domain receptor; CD309; FLK1; FLK-1; KDR; KRD-1; Ly73; VEGFR; VEGFR2; VEGFR-2 | KINOMEscan | Wild Type; Partial length | |||
| 200459 | VRK2 | 200459 | Q86Y07 | Serine/threonine-protein kinase VRK2; vaccinia related kinase 2; VRK2 | KINOMEscan | Wild Type; Partial length | |||
| 200460 | WEE1 | 200460 | P30291 | Wee1-like protein kinase; DKFZp686I18166; FLJ16446; WEE1; WEE1A; WEE1hu | KINOMEscan | Wild Type; Partial length | |||
| 200461 | WEE2 | 200461 | P0C1S8 | Wee1-like protein kinase 2; FLJ16107; WEE1B; WEE2 | KINOMEscan | Wild Type; Partial length | |||
| 200462 | YANK1 | 200462 | Q8WU08 | Serine/threonine kinase 32A; MGC22688; STK32A; YANK1 | KINOMEscan | Wild Type; Full length | |||
| 200463 | YANK2 | 200463 | Q9NY57 | Serine/threonine kinase 32B; HSA250839; STK32; STK32B; STKG6; YANK2 | KINOMEscan | Wild Type; Full length | |||
| 200464 | YANK3 | 200464 | Q86UX6 | Serine/threonine kinase 32C; MGC23665; PKE; RP11-140A10.1; STK32C; YANK3 | KINOMEscan | Wild Type; Partial length | |||
| 200465 | YES | 200465 | P07947 | Tyrosine-protein kinase Yes; Proto-oncogene tyrosine-protein kinase Yes | KINOMEscan | Wild Type; Partial length | |||
| 200466 | YSK1 | 200466 | O00506 | Serine/threonine-protein kinase 26 | KINOMEscan | Wild Type; Partial length | |||
| 200467 | YSK4 | 200467 | Q56UN5 | YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae); FLJ23074; MAP3K8; RCK; YSK4 | KINOMEscan | Wild Type; Partial length | |||
| 200468 | MLTK | 200468 | Q9NYL2 | Mitogen-activated protein kinase kinase kinase MLT; sterile alpha motif and leucine zipper containing kinase AZK; AZK; MLK7; mlklak; MLT; MLTK; MRK; pk; ZAK | KINOMEscan | Wild Type; Partial length | |||
| 200469 | ZAP70 | 200469 | P43403 | Tyrosine-protein kinase ZAP-70; Zeta-chain (TCR) associated protein kinase 70kDa; FLJ17670; FLJ17679; SRK; STD; TZK; ZAP70; ZAP-70 | KINOMEscan | Wild Type; Partial length | |||
| 200470 | BUB1 | 200470 | Budding uninhibited by benzimidazoles 1 homolog (yeast); BUB1A; BUB1L; hBUB1 | KINOMEscan | |||||
| 200471 | CSF1R-autoinhibited | 200471 | P07333 | Colony stimulating factor 1 receptor; CD115; C-FMS; CSF1R; CSF-1R; CSF-1-R; CSFR; FIM2; FIM-2; FMS; Fms/CSFR | KINOMEscan | ||||
| 200472 | FLT3-autoinhibited | 200472 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ||||
| 200473 | HASP | 200473 | Q8TF76 | Serine/threonine-protein kinase haspin; germ cell associated 2 (haspin); GSG2; HASPIN | KINOMEscan | ||||
| 200474 | KIT-autoinhibited | 200474 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | ||||
| 200475 | RSK2(Kin.Dom.2-C-terminal) | 200475 | P51812 | Ribosomal protein S6 kinase alpha 3; KS6A3; S6K-alpha-3; p90-RSK 3; MAPKAPK-1b; pp90RSK2 | KINOMEscan | Kin.Dom.2-C-terminal | |||
| 200476 | SGK1 | 200476 | O00141 | Serine/threonine-protein kinase Sgk1; serum/glucocorticoid regulated kinase 1; SGK | KINOMEscan | ||||
| 200477 | WNK1 | 200477 | Q9H4A3 | WNK lysine deficient protein kinase 1; KDP; PSK; p65; HSN2; HSAN2; PRKWNK1 | KINOMEscan | ||||
| 200478 | WNK3 | 200478 | Q9BYP7 | WNK lysine deficient protein kinase 3; PRKWNK3 | KINOMEscan | ||||
| 200479 | ALK(C1156Y) | 200479 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | C1156Y | |||
| 200480 | ALK(L1196M) | 200480 | Q9UM73 | Anaplastic lymphoma receptor tyrosine kinase; ALK; CD246; NBLST3; TFG/ALK | KINOMEscan | L1196M | |||
| 200481 | NEK10 | 200481 | Q6ZWH5 | NIMA (never in mitosis gene a)- related kinase 10 | KINOMEscan | ||||
| 200482 | Akt-1 | 200482 | P31749 | RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha | |||||
| 200483 | Akt-2 | 200483 | P31751 | RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta | |||||
| 200484 | Akt-3 | 200484 | Q9Y243 | RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2 | |||||
| 200485 | ALK | 200485 | Q9UM73 | ALK tyrosine kinase receptor; anaplastic lymphoma receptor tyrosine kinase | |||||
| 200486 | AMPK-alpha1 | 200486 | Q13131 | Protein kinase, AMP-activated, alpha 2 catalytic subunit | |||||
| 200487 | AMPK-alpha2 | 200487 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2; protein kinase, AMP-activated, alpha 2 catalytic subunit | |||||
| 200488 | ATM | 200488 | Q13315 | Serine-protein kinase ATM | |||||
| 200489 | Aurora kinase A | 200489 | O14965 | Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A | |||||
| 200490 | Aurora kinase B | 200490 | Q96GD4 | Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B | |||||
| 200491 | Aurora kinase C | 200491 | Q9UQB9 | Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 protein 2; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C | |||||
| 200492 | BAD | 200492 | Q92934 | Bcl2 antagonist of cell death | |||||
| 200493 | BCL2 | 200493 | P10415 | Apoptosis regulator Bcl-2 | |||||
| 200494 | BRAF | 200494 | P15056 | Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1; BRAF1; RAFB1 | |||||
| 200495 | c-Abl | 200495 | P00519 | Tyrosine-protein kinase ABL1 | |||||
| 200496 | CDC2 [deprecated record] | 200496 | P06493 | Cyclin-dependent kinase 1 | |||||
| 200497 | Cdc25 | 200497 | Q13972 | Ras-specific guanine nucleotide-releasing factor 1 | |||||
| 200498 | CDK1 | 200498 | P06493 | Cyclin-dependent kinase 1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase | |||||
| 200499 | CHK1 | 200499 | O14757 | Serine/threonine-protein kinase Chk1; CHK1 checkpoint homolog | |||||
| 200500 | CHK2 | 200500 | O96017 | Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog |