Proteins
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| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200101 | KC1G2 | 200101 | P78368 | Casein kinase I isoform gamma-2; Casein kinase 1, gamma 2; CK1g2; CSNK1G2 | KINOMEscan | Wild Type; Full length | |||
| 200102 | CSNK1G3 | 200102 | Q9Y6M4 | Casein kinase 1, gamma 3; CK1g3; CSNK1G3 | KINOMEscan | Wild Type; Full length | |||
| 200103 | CSNK2A1 | 200103 | P68400 | Casein kinase 2, alpha 1 polypeptide; CK2A1; CKII; CSNK2A1 | KINOMEscan | Wild Type; Full length | |||
| 200104 | CSNK2A2 | 200104 | P19784 | Casein kinase 2, alpha prime polypeptide; CK2A2; CSNK2A1; CSNK2A2; FLJ43934 | KINOMEscan | Wild Type; Full length | |||
| 200105 | CTK | 200105 | P42679 | Megakaryocyte-associated tyrosine kinase; CHK; CTK; DKFZp434N1212; HHYLTK; HYL; HYLTK; Lsk; MATK; MGC1708; MGC2101 | KINOMEscan | Wild Type; Full length | |||
| 200106 | DAPK1 | 200106 | P53355 | Death-associated protein kinase 1; DAPK; DAPK1; DKFZp781I035 | KINOMEscan | Wild Type; Partial length | |||
| 200107 | DAPK2 | 200107 | Q9UIK4 | Death-associated protein kinase 2; DAPK2; DRP1; DRP-1; MGC119312 | KINOMEscan | Wild Type; Full length | |||
| 200108 | DAPK3 | 200108 | O43293 | Death-associated protein kinase 3; DAPK3; FLJ36473; ZIP; ZIPK | KINOMEscan | Wild Type; Partial length | |||
| 200109 | DCLK1 | 200109 | O15075 | Serine/threonine-protein kinase DCLK1; CL1; CLICK1; DCAMKL1; DCDC3A; DCLK; DCLK1; KIAA0369 | KINOMEscan | Wild Type; Partial length | |||
| 200110 | DCAMKL2 | 200110 | Q8N568 | Doublecortin-like kinase 2; CL2; CLICK2; CLICK-II; CLIK2; DCAMKL2; DCDC3; DCDC3B; DCK2; DCLK2; DKFZp761l032; MGC45428 | KINOMEscan | Wild Type; Partial length | |||
| 200111 | DCAMKL3 | 200111 | Q9C098 | Doublecortin-like kinase 3; CLR; DCAMKL3; DCDC3C; DCK3; DCLK3; KIAA1765 | KINOMEscan | Wild Type; Partial length | |||
| 200112 | DDR1 | 200112 | Q08345 | Discoidin domain receptor tyrosine kinase 1; CAK; CD167; DDR; DDR1; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE | KINOMEscan | Wild Type; Partial length | |||
| 200113 | DDR2 | 200113 | Q16832 | Discoidin domain receptor tyrosine kinase 2; DDR2; MIG20a; NTRKR3; TKT; TYRO10 | KINOMEscan | Wild Type; Partial length | |||
| 200114 | M3K12 | 200114 | Q12852 | Mitogen-activated protein kinase kinase kinase 12; Dual leucine zipper bearing kinase; DLK; MAP3K12; MEKK12; MUK; ZPK; ZPKP1 | KINOMEscan | Wild Type; Full length | |||
| 200115 | DMPK | 200115 | Q09013 | Myotonin-protein kinase; Dystrophia myotonica-protein kinase; DM; DM1; DM1PK; DMK; MDPK; MT-PK | KINOMEscan | Wild Type; Partial length | |||
| 200116 | DMPK2 | 200116 | Q6DT37 | CDC42 binding protein kinase gamma (DMPK-like); CDC42BPG; DMPK2; HSMDPKIN; KAPPA-200; MRCKgamma | KINOMEscan | Wild Type; Partial length | |||
| 200117 | DRAK1 | 200117 | Q9UEE5 | Serine/threonine kinase 17a; DRAK1; STK17A | KINOMEscan | Wild Type; Partial length | |||
| 200118 | DRAK2 | 200118 | O94768 | Serine/threonine kinase 17b; DRAK2; STK17B | KINOMEscan | Wild Type; Full length | |||
| 200119 | DYRK1A | 200119 | Q13627 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; DYRK; DYRK1; DYRK1A; HP86; MNB; MNBH | KINOMEscan | Wild Type; Partial length | |||
| 200120 | DYRK1B | 200120 | Q9Y463 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; DYRK1B; MIRK | KINOMEscan | Wild Type; Full length | |||
| 200121 | DYRK2 | 200121 | Q92630 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; DYRK2; FLJ21217; FLJ21365 | KINOMEscan | Wild Type; Full length | |||
| 200122 | EGFR | 200122 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | Wild Type; Partial length | |||
| 200123 | EGFR(E746-A750del) | 200123 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | E746-A750del | Mutation (E746-A750del); Partial length | ||
| 200124 | EGFR(G719C) | 200124 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | G719C | Mutation (G719C); Partial length | ||
| 200125 | EGFR(G719S) | 200125 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | G719S | Mutation (G719S); Partial length | ||
| 200126 | EGFR(L747-E749del, A750P) | 200126 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-E749del, A750P | Mutation (L747-E749del, A750P); Partial length | ||
| 200127 | EGFR(L747-S752del, P753S) | 200127 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-S752del, P753S | Mutation (L747-S752del, P753S); Partial length | ||
| 200128 | EGFR(L747-T751del,Sins) | 200128 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-T751del,Sins | Mutation (L747-T751del,Sins); Partial length | ||
| 200129 | EGFR(L858R) | 200129 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R | Mutation (L858R); Partial length | ||
| 200130 | EGFR(L858R,T790M) | 200130 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R,T790M | Mutation (L858R,T790M); Partial length | ||
| 200131 | EGFR(L861Q) | 200131 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L861Q | Mutation (L861Q); Partial length | ||
| 200132 | EGFR(S752-I759del) | 200132 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | S752-I759del | Mutation (S752-I759del); Partial length | ||
| 200133 | EGFR(T790M) | 200133 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | T790M | Mutation (T790M); Partial length | ||
| 200134 | EIF2AK1 | 200134 | Q9BQI3 | Eukaryotic translation initiation factor 2-alpha kinase 1; EIF2AK1; HCR; HRI; KIAA1369 | KINOMEscan | Wild Type; Partial length | |||
| 200135 | EPHA1 | 200135 | P21709 | EPH receptor A1; EPH; EPHA1; EPHT; EPHT1; MGC163163 | KINOMEscan | Wild Type; Partial length | |||
| 200136 | EPHA2 | 200136 | P29317 | EPH receptor A2; ARCC2; ECK; EPHA2 | KINOMEscan | Wild Type; Partial length | |||
| 200137 | EPHA3 | 200137 | P29320 | EPH receptor A3; EK4; EPHA3; ETK; ETK1; HEK; HEK4; TYRO4 | KINOMEscan | Wild Type; Partial length | |||
| 200138 | EPHA4 | 200138 | P54764 | EPH receptor A4; EPHA4; HEK8; SEK; TYRO1 | KINOMEscan | Wild Type; Partial length | |||
| 200139 | EPHA5 | 200139 | P54756 | EPH receptor A5; CEK7; EHK1; EPHA5; HEK7; TYRO4 | KINOMEscan | Wild Type; Partial length | |||
| 200140 | EPHA6 | 200140 | Q9UF33 | EPH receptor A6; DKFZp434C1418; EPA6; EPHA6; FLJ35246; PRO57066 | KINOMEscan | Wild Type; Partial length | |||
| 200141 | EPHA7 | 200141 | Q15375 | EPH receptor A7; EHK3; EPHA7; HEK11 | KINOMEscan | Wild Type; Partial length | |||
| 200142 | EPHA8 | 200142 | P29322 | EPH receptor A8; EEK; EK3; EPHA8; HEK3; KIAA1459 | KINOMEscan | Wild Type; Partial length | |||
| 200143 | EPHB1 | 200143 | P54762 | Ephrin type-B receptor 1; ELK; EPHB1; EPHT2; FLJ37986; Hek6; NET | KINOMEscan | Wild Type; Partial length | |||
| 200144 | EPHB2 | 200144 | P29323 | Ephrin type-B receptor 2; CAPB; DRT; EK5; EPHB2; EPHT3; ERK; Hek5; MGC87492; PCBC; Tyro5 | KINOMEscan | Wild Type; Partial length | |||
| 200145 | EPHB3 | 200145 | P54753 | Ephrin type-B receptor 3; EPHB3; ETK2; HEK2; TYRO6 | KINOMEscan | Wild Type; Partial length | |||
| 200146 | EPHB4 | 200146 | P54760 | Ephrin type-B receptor 4; EPHB4; HTK; MYK1; TYRO11 | KINOMEscan | Wild Type; Partial length | |||
| 200147 | EPHB6 | 200147 | O15197 | EPH receptor B6; EPHB6; HEP; MGC129910; MGC129911 | KINOMEscan | Wild Type; Partial length | |||
| 200148 | ERBB2 | 200148 | P04626 | Receptor tyrosine-protein kinase erbB-2; CD340; ERBB2; HER2; HER-2; HER-2/neu; MLN 19; NEU; NGL; TKR1 | KINOMEscan | Wild Type; Partial length | |||
| 200149 | ERBB3 | 200149 | P21860 | Receptor tyrosine-protein kinase erbB-3; Proto-oncogene-like protein c-ErbB-3; HER3 | KINOMEscan | Wild Type; Partial length | |||
| 200150 | ERBB4 | 200150 | Q15303 | Receptor tyrosine-protein kinase erbB-4; HER4; MGC138404; p180erbB4 | KINOMEscan | Wild Type; Partial length | |||
| 200151 | MK03 | 200151 | P27361 | Mitogen-activated protein kinase 3; ERK1; HS44KDAP; HUMKER1A; MAPK3; MGC20180; P44ERK1; P44MAPK; PRKM3 | KINOMEscan | Wild Type; Full length | |||
| 200152 | MK01 | 200152 | P28482 | Mitogen-activated protein kinase 1; ERK; ERK2; ERT1; MAPK1; MAPK2; p38; p40; p41; p41mapk; P42MAPK; PRKM1; PRKM2 | KINOMEscan | Wild Type; Full length | |||
| 200153 | ERK3 | 200153 | Q16659 | Mitogen-activated protein kinase 6; DKFZp686F03189; ERK3; HsT17250; MAPK6; p97MAPK; PRKM6 | KINOMEscan | Wild Type; Partial length | |||
| 200154 | ERK4 | 200154 | P31152 | Mitogen-activated protein kinase 4; ERK3; Erk4; MAPK4; p63MAPK; PRKM4 | KINOMEscan | Wild Type; Partial length | |||
| 200155 | ERK5 | 200155 | Q13164 | Mitogen-activated protein kinase 7; BMK1; ERK4; ERK5; MAPK7; PRKM7 | KINOMEscan | Wild Type; Partial length | |||
| 200156 | ERK8 | 200156 | Q8TD08 | Mitogen-activated protein kinase 15; ERK7; ERK8; MAPK15 | KINOMEscan | Wild Type; Partial length | |||
| 200157 | ERN1 | 200157 | O75460 | Endoplasmic reticulum to nucleus signaling 1; ERN1; FLJ30999; hIRE1p; IRE1; IRE1a; IRE1P; MGC163277; MGC163279 | KINOMEscan | Wild Type; Partial length | |||
| 200158 | FAK1 | 200158 | Q05397 | PTK2 protein tyrosine kinase 2; FADK; FAK; FAK1; FRNK; pp125FAK; PTK2 | KINOMEscan | Wild Type; Partial length | |||
| 200159 | FER | 200159 | P16591 | Fer (fps/fes related) tyrosine kinase; FER; TYK3 | KINOMEscan | Wild Type; Partial length | |||
| 200160 | FES | 200160 | P07332 | Feline sarcoma oncogene; FES; FPS | KINOMEscan | Wild Type; Partial length | |||
| 200161 | FGFR1 | 200161 | P11362 | Fibroblast growth factor receptor 1; BFGFR; CD331; CEK; FGFBR; FGFR1; FLG; FLJ99988; FLT2; HBGFR; KAL2; N-SAM; OGD | KINOMEscan | Wild Type; Partial length | |||
| 200162 | FGFR2 | 200162 | P21802 | Fibroblast growth factor receptor 2; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; FGFR2; FLJ98662; JWS; KGFR; K-SAM; TK14; TK25 | KINOMEscan | Wild Type; Partial length | |||
| 200163 | FGFR3 | 200163 | P22607 | Fibroblast growth factor receptor 3; ACH; CD333; CEK2; FGFR3; HSFGFR3EX; JTK4 | KINOMEscan | Wild Type; Partial length | |||
| 200164 | FGFR3(G697C) | 200164 | P22607 | Fibroblast growth factor receptor 3; ACH; CD333; CEK2; FGFR3; HSFGFR3EX; JTK4 | KINOMEscan | G697C | Mutation (G697C); Partial length | ||
| 200165 | FGFR4 | 200165 | P22455 | Fibroblast growth factor receptor 4; CD334; FGFR4; JTK2; MGC20292; TKF | KINOMEscan | Wild Type; Partial length | |||
| 200166 | FGR | 200166 | P09769 | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; c-fgr; c-src2; FGR; FLJ43153; MGC75096; p55c-fgr; p55-Fgr; p58c-fgr; SRC2 | KINOMEscan | Wild Type; Partial length | |||
| 200167 | VGFR1 | 200167 | P17948 | Vascular endothelial growth factor receptor 1; fms-related tyrosine kinase 1; vascular permeability factor receptor; FLT; FLT1; VEGFR1 | KINOMEscan | Wild Type; Partial length | |||
| 200168 | FLT3 | 200168 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | Wild Type; Partial length | |||
| 200169 | FLT3(D835H) | 200169 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835H | Mutation (D835H); Partial length | ||
| 200170 | FLT3(D835Y) | 200170 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835Y | Mutation (D835Y); Partial length | ||
| 200171 | FLT3(ITD) | 200171 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD | Mutation (ITD); Partial length | ||
| 200172 | FLT3(K663Q) | 200172 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | K663Q | Mutation (K663Q); Partial length | ||
| 200173 | FLT3(N841I) | 200173 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | N841I | Mutation (N841I); Partial length | ||
| 200174 | FLT3(R834Q) | 200174 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | R834Q | Mutation (R834Q); Partial length | ||
| 200175 | FLT4 | 200175 | P35916 | Fms-related tyrosine kinase 4; FLT4; FLT41; LMPH1A; PCL; VEGFR3 | KINOMEscan | Wild Type; Partial length | |||
| 200176 | FRK | 200176 | P42685 | Tyrosine-protein kinase FRK; Fyn-related kinase; FRK; GTK; PTK5; RAK | KINOMEscan | Wild Type; Partial length | |||
| 200177 | FYN | 200177 | P06241 | FYN oncogene related to SRC, FGR, YES; FYN; MGC45350; SLK; SYN | KINOMEscan | Wild Type; Partial length | |||
| 200178 | GAK | 200178 | O14976 | Cyclin G associated kinase; FLJ16629; FLJ40395; GAK; MGC99654 | KINOMEscan | Wild Type; Partial length | |||
| 200179 | GCN2(Kin.Dom.2,S808G) | 200179 | Q9P2K8 | Eukaryotic translation initiation factor 2 alpha kinase 4; EIF2AK4; GCN2; KIAA1338 | KINOMEscan | S808G | Kin.Dom.2 | Wild Type; Partial length | |
| 200180 | GRK1 | 200180 | Q15835 | G protein-coupled receptor kinase 1; GPRK1; GRK1; RHODK; RHODK/GRK1; RHOK; RK | KINOMEscan | Wild Type; Full length | |||
| 200181 | GRK4 | 200181 | P32298 | G protein-coupled receptor kinase 4; GPRK2L; GPRK4; GRK4; GRK4a; IT11 | KINOMEscan | Wild Type; Full length | |||
| 200182 | GRK7 | 200182 | Q8WTQ7 | G protein-coupled receptor kinase 7; GPRK7; GRK7 | KINOMEscan | Wild Type; Full length | |||
| 200183 | GSK3A | 200183 | P49840 | Glycogen synthase kinase 3 alpha; DKFZp686D0638; GSK3A; GSK3alpha; GSK3-alpha | KINOMEscan | Wild Type; Full length | |||
| 200184 | GSK3B | 200184 | P49841 | Glycogen synthase kinase 3 beta; GSK3B; GSK3beta; GSK3-beta | KINOMEscan | Wild Type; Full length | |||
| 200185 | HCK | 200185 | P08631 | Hemopoietic cell kinase; HCK; JTK9 | KINOMEscan | Wild Type; Full length | |||
| 200186 | HIPK1 | 200186 | Q86Z02 | Homeodomain interacting protein kinase 1; HIPK1; KIAA0630; MGC26642; MGC33446; MGC33548; Myak; Nbak2 | KINOMEscan | Wild Type; Partial length | |||
| 200187 | HIPK2 | 200187 | Q9H2X6 | Homeodomain interacting protein kinase 2; DKFZp686K02111; FLJ23711; HIPK2; PRO0593 | KINOMEscan | Wild Type; Partial length | |||
| 200188 | HIPK3 | 200188 | Q9H422 | Homeodomain interacting protein kinase 3; DYRK6; FIST3; HIPK3; PKY; YAK1 | KINOMEscan | Wild Type; Partial length | |||
| 200189 | HIPK4 | 200189 | Q8NE63 | Homeodomain interacting protein kinase 4; FLJ32818; HIPK4 | KINOMEscan | Wild Type; Partial length | |||
| 200190 | M4K1 | 200190 | Q92918 | Mitogen-activated protein kinase kinase kinase kinase 1; HPK1; MAP4K1 | KINOMEscan | Wild Type; Full length | |||
| 200191 | HUNK | 200191 | P57058 | Hormonally up-regulated Neu-associated kinase; HUNK | KINOMEscan | Wild Type; Partial length | |||
| 200192 | ICK | 200192 | Q9UPZ9 | Intestinal cell (MAK-like) kinase; ECO; ICK; KIAA0936; LCK2; MGC46090; MRK | KINOMEscan | Wild Type; Partial length | |||
| 200193 | IGF1R | 200193 | P08069 | Insulin-like growth factor 1 receptor; CD221; IGF1R; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216 | KINOMEscan | Wild Type; Partial length | |||
| 200194 | IKKA | 200194 | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | KINOMEscan | Wild Type; Full length | |||
| 200195 | IKKB | 200195 | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | KINOMEscan | Wild Type; Full length | |||
| 200196 | IKKE | 200196 | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | KINOMEscan | Wild Type; Full length | |||
| 200197 | INSR | 200197 | P06213 | Insulin receptor; CD220; HHF5; INSR; IR | KINOMEscan | Wild Type; Partial length | |||
| 200198 | INSRR | 200198 | P14616 | Insulin receptor-related receptor; INSRR; IRR | KINOMEscan | Wild Type; Partial length | |||
| 200199 | IRAK1 | 200199 | P51617 | Interleukin-1 receptor-associated kinase 1 | KINOMEscan | Wild Type; Partial length | |||
| 200200 | IRAK3 | 200200 | Q9Y616 | Interleukin-1 receptor-associated kinase 3; ASRT5; FLJ13601; IRAK3; IRAKM | KINOMEscan | Wild Type; Partial length |