Proteins
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
201221 | M3K13 | 201221 | O43283 | Mitogen-activated protein kinase kinase kinase 13; LZK; MAP3K13; MEKK13; MGC133196 | KiNativ | ||||
201222 | M3K12 | 201222 | Q12852 | Mitogen-activated protein kinase kinase kinase 12; Dual leucine zipper bearing kinase; DLK; MAP3K12; MEKK12; MUK; ZPK; ZPKP1 | KiNativ | ||||
201223 | M3K2 | 201223 | Q9Y2U5 | Mitogen-activated protein kinase kinase kinase 2; MAP3K2; MEKK2; MEKK2/MAP3K2; MEKK2B | KiNativ | ||||
201224 | M4K3 | 201224 | Q8IVH8 | Mitogen-activated protein kinase kinase kinase kinase 3; GLK; KHS2; MAP4K3; MAPKKKK3; MEKKK3; RAB8IPL1 | KiNativ | ||||
201230 | M3K6 | 201230 | O95382 | Mitogen-activated protein kinase kinase kinase 6; ASK2; MAP3K6; MAPKKK6; MEKK6; MEKK6/MAP3K6; MGC125653; MGC20114 | KiNativ | ||||
201231 | MARK1,MARK2 | 201231 | Q7KZI7 | Serine/threonine-protein kinase MARK2; MAP/microtubule affinity-regulating kinase 2; EMK1; EMK-1; MGC99619; PAR-1; Par1b | KiNativ | ||||
201232 | MARK2 | 201232 | Q7KZI7 | Serine/threonine-protein kinase MARK2; MAP/microtubule affinity-regulating kinase 2; EMK1; EMK-1; MGC99619; PAR-1; Par1b | KiNativ | ||||
201233 | MARK4 | 201233 | Q96L34 | MAP/microtubule affinity-regulating kinase 4; FLJ90097; KIAA1860; MARKL1; Nbla00650 | KiNativ | ||||
201235 | MELK | 201235 | Q14680 | Maternal embryonic leucine zipper kinase; HPK38; KIAA0175 | KiNativ | ||||
201236 | MER,TYRO3 | 201236 | Q12866 | Proto-oncogene tyrosine-protein kinase MER precursor | KiNativ | ||||
201237 | MK09 | 201237 | P45984 | Mitogen-activated protein kinase 9; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-55; MAPK9; p54a; p54aSAPK; PRKM9; SAPK | KiNativ | ||||
201240 | MP2K2 | 201240 | P36507 | Dual specificity mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; FLJ26075; MAP2K2; MAPKK2; MEK2; MEK2/MAP2K2; MKK2; PRKMK2 | KiNativ | ||||
201241 | MP2K7 | 201241 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | KiNativ | ||||
201242 | MST4,YSK1 | 201242 | O00506 | Serine/threonine-protein kinase 25 | KiNativ | ||||
201243 | NEK2 | 201243 | P51955 | Serine/threonine-protein kinase Nek2; NIMA (never in mitosis gene a)-related kinase 2; HsPK21; NEK2; NEK2A; NLK1 | KiNativ | ||||
201247 | NLK | 201247 | Q9UBE8 | Serine/threonine-protein kinase NLK; Nemo-like kinase; DKFZp761G1211; FLJ21033 | KiNativ | ||||
201248 | NUAK1 | 201248 | O60285 | NUAK family, SNF1-like kinase, 1; ARK5; KIAA0537; NUAK1 | KiNativ | ||||
201249 | PASK | 201249 | Q96RG2 | PAS domain-containing serine/threonine-protein kinase | KiNativ | ||||
201250 | PDHK1 | 201250 | Q15118 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precursor | KiNativ | ||||
201251 | PI42C | 201251 | Q8TBX8 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; FLJ22055; PIP4K2C; PIP5K2C | KiNativ | ||||
201252 | PI42C | 201252 | Q8TBX8 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; FLJ22055; PIP4K2C; PIP5K2C | KiNativ | ||||
201253 | PI4K2A | 201253 | Q9BTU6 | Phosphatidylinositol 4-kinase type II | KiNativ | ||||
201254 | P4K2B | 201254 | Q8TCG2 | Phosphatidylinositol 4-kinase type 2-beta | KiNativ | ||||
201255 | P3C2A | 201255 | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | KiNativ | ||||
201257 | PIP5K2A (PIP4K2A) | 201257 | P48426 | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII | KiNativ | ||||
201258 | PKMYT1 | 201258 | Q99640 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Protein kinase, membrane associated tyrosine/threonine 1; DKFZp547K1610; FLJ20093; MYT1 | KiNativ | ||||
201261 | RIPK4 | 201261 | P57078 | Receptor-interacting serine-threonine kinase 4; ANKK2; ANKRD3; DIK; MGC129992; MGC129993; PKK; RIP4 | KiNativ | ||||
201262 | RSK2 domain1 | 201262 | P51812 | Ribosomal protein S6 kinase alpha 3 | KiNativ | domain1 | |||
201263 | SGK1 | 201263 | O00141 | Serine/threonine-protein kinase Sgk1; serum/glucocorticoid regulated kinase 1; SGK | KiNativ | ||||
201265 | SGK3 | 201265 | Q96BR1 | Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid-regulated kinase 3; CISK; DKFZp781N0293; SGKL | KiNativ | ||||
201266 | SIK3 | 201266 | Q9Y2K2 | Serine/threonine-protein kinase SIK3; SIK family kinase 3; FLJ12240; KIAA0999; L19; QSK | KiNativ | ||||
201267 | SMG1 | 201267 | Q96Q15 | Serine/threonine-protein kinase SMG1 | KiNativ | ||||
201268 | STK33 | 201268 | Q9BYT3 | Serine/threonine kinase 33 | KiNativ | ||||
201269 | STK39 | 201269 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase; serine threonine kinase 39 (STE20/SPS1 homolog, yeast); DCHT; DKFZp686K05124; PASK; SPAK; STLK3 | KiNativ | ||||
201272 | SYK | 201272 | P43405 | Tyrosine-protein kinase SYK; spleen tyrosine kinase; p72-Syk; DKFZp313N1010; FLJ25043; FLJ37489 | KiNativ | ||||
201273 | TAOK3 | 201273 | Q9H2K8 | Serine/threonine-protein kinase TAO3; TAO kinase 3; DKFZp666H245; DPK; FLJ31808; JIK; MAP3K18; TAO3 | KiNativ | ||||
201276 | TYK2(Kin.Dom.2) | 201276 | P29597 | Non-receptor tyrosine-protein kinase TYK2; Tyrosine kinase 2; JTK1; TYK2 | KiNativ | Kin.Dom.2 | |||
201279 | Wnk1,Wnk2 | 201279 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | KiNativ | ||||
201281 | YES | 201281 | P07947 | Tyrosine-protein kinase Yes; Proto-oncogene tyrosine-protein kinase Yes | KiNativ | ||||
201282 | ZAP70 | 201282 | P43403 | Tyrosine-protein kinase ZAP-70; Zeta-chain (TCR) associated protein kinase 70kDa; FLJ17670; FLJ17679; SRK; STD; TZK | KiNativ | ||||
201283 | ZAP70 | 201283 | P43403 | Tyrosine-protein kinase ZAP-70; Zeta-chain (TCR) associated protein kinase 70kDa; FLJ17670; FLJ17679; SRK; STD; TZK | KiNativ | ||||
201284 | TNF10 | 201284 | P50591 | Tumor necrosis factor ligand superfamily member 10; TRAIL; Apo-2L | R&D System | ||||
201285 | TNF-a | 201285 | P01375 | Tumor Necrosis Factor-α; TNF-alpha; Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin | PeproTech | ||||
201286 | IL-1 alpha | 201286 | P01583 | Interleukin 1; Hematopoietin-1; Lymphocyte-activating factor (LAF); Endogenous Pyrogen (EP); Leukocyte Endogenous Mediator (LEM); Mononuclear Cell Factor (MCF) | PeproTech | ||||
201287 | IL-6 | 201287 | P05231 | Interleukin 6; 26 kDa protein, IFN-β2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2 | PeproTech | ||||
201288 | IL-17A | 201288 | Q16552 | Interleukin-17A (IL-17A) (IL-17); Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8) | PeproTech | ||||
201289 | EGF | 201289 | P01133 | Epidermal Growth Factor; Urogastrone; URG | PeproTech | ||||
201290 | IGF-I | 201290 | P05019 | Insulin-like growth factor I; Mechano growth factor; MGF; Somatomedin-C | PeproTech | ||||
201291 | Adiponectin | 201291 | Q15848 | 30 kDa adipocyte complement-related protein; Acrp-30; GBP-28; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; APM-1; Gelatin-binding protein; AdipoQ | PeproTech | ||||
201292 | Leptin | 201292 | P41159 | Obese protein (OB); Obesity factor | PeproTech | ||||
201293 | Visfatin | 201293 | P43490 | Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt); Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; PBEF: Visfatin | PeproTech | ||||
201294 | H3 (pS10) | 201294 | P68431 | pS10 | |||||
201295 | p21 | 201295 | P38936 | Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6 | |||||
201296 | KI-67 | 201296 | P46013 | Antigen KI-67 | |||||
201297 | Rb (pS807; pS811) | 201297 | P06400 | pS807; pS811 | |||||
201298 | S6 (pS235; pS236) | 201298 | P62753 | pS235; pS236 | |||||
201299 | S6 (pS240; pS244) | 201299 | P62753 | pS240; pS244 | |||||
201300 | Ep-CAM | 201300 | P16422 | Epithelial cell adhesion molecule; Ep-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; CD326 | |||||
201301 | Lamin-A/C | 201301 | P02545 | Prelamin-A/C; Lamin-A/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32 | |||||
201302 | PCNA | 201302 | P12004 | Proliferating cell nuclear antigen; Cyclin | |||||
201303 | ERK-1 (pT202; pY204) | 201303 | P27361 | pT202; pY204 | |||||
201304 | ERK-2 (pT185; pY187) | 201304 | P28482 | pT185; pY187 | |||||
201305 | K4 | 201305 | P19013 | Keratin, type II cytoskeletal 4; Cytokeratin-4; CK-4; Keratin-4; Type-II keratin Kb4 | |||||
201306 | K5 | 201306 | P13647 | Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; Type-II keratin Kb5 | |||||
201307 | K6A | 201307 | P02538 | Keratin, type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Cytokeratin-6D; CK-6D; Keratin-6A; Type-II keratin Kb6; Hom s 5 | |||||
201308 | K6B | 201308 | P04259 | Keratin, type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; Type-II keratin Kb10 | |||||
201309 | K6C | 201309 | P48668 | Keratin, type II cytoskeletal 6C; Cytokeratin-6C; CK-6C; Cytokeratin-6E; CK-6E; Keratin K6h; Keratin-6C; Type-II keratin Kb12 | |||||
201310 | K8 | 201310 | P05787 | Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Type-II keratin Kb8 | |||||
201311 | K10 | 201311 | P13645 | Keratin, type I cytoskeletal 10; Cytokeratin-10; CK-10 | |||||
201312 | K13 | 201312 | P13646 | Keratin, type I cytoskeletal 13; Cytokeratin-13; CK-13 | |||||
201313 | K18 | 201313 | P05783 | Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18 | |||||
201314 | H2A.X (pS139) | 201314 | P16104 | pS139 | |||||
201315 | SOX-2 | 201315 | P48431 | Transcription factor SOX-2 | |||||
201316 | Beta-actin | 201316 | P60709 | Actin, cytoplasmic 1 | |||||
201317 | Tubulin beta chain | 201317 | P07437 | Tubulin beta-5 chain | |||||
201318 | c-Jun (pS73) | 201318 | P05412 | pS73 | |||||
201319 | c-Jun | 201319 | P05412 | Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 | |||||
201320 | TNF-a | 201320 | P01375 | Tumor Necrosis Factor-α; TNF-alpha; Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin | |||||
201321 | TNF10 | 201321 | P50591 | Tumor necrosis factor ligand superfamily member 10; TRAIL; Apo-2L | Sigma | Recombinant human TRAIL is a 168 amino acid polypeptide (19.6 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL/Apo2L protein,1 expressed in E. coli. 1. Wiley, S.R. et al., Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity, 3, 673-682 (1995). [source: Sigma Aldrich] | |||
201322 | rabbit gamma immunoglobin heavy and light chains | 201322 | rabbit IgG(H+L)
| ||||||
201323 | mouse gamma immunoglobin heavy and light chains | 201323 | mouse IgG(H+L)
| ||||||
201324 | CAMK1B | 201324 | Q6P2M8 | Calcium/calmodulin-dependent protein kinase type 1B; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase; CaM kinase I beta | KINOMEscan | ||||
201325 | FLT3(D835V) | 201325 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835V | |||
201326 | FLT3(ITD,D835V) | 201326 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD,D835V | |||
201327 | FLT3(ITD,F691L) | 201327 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD,F691L | |||
201328 | BARK1 | 201328 | P25098 | Beta-adrenergic receptor kinase 1; GRK2 | KINOMEscan | ||||
201329 | BARK2 | 201329 | P35626 | Beta-adrenergic receptor kinase 2; GRK3 | KINOMEscan | ||||
201330 | FYV1 | 201330 | Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase; PIKfyve | KINOMEscan | ||||
201331 | TSSK3 | 201331 | Q96PN8 | Testis-specific serine/threonine-protein kinase 3; TSK-3 | KINOMEscan | ||||
201332 | PIK3C3 | 201332 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3; PI3-kinase type 3; VPS34 | KINOMEscan | ||||
201333 | WNK2 | 201333 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | KINOMEscan | ||||
201334 | WNK4 | 201334 | Q96J92 | Serine/threonine-protein kinase WNK4 | KINOMEscan | ||||
201335 | Rb (pS807) | 201335 | P06400 | pS807 | |||||
201336 | Rb (pS811) | 201336 | P06400 | pS811 | |||||
201337 | ERK-1 (pT202) | 201337 | P27361 | pT202 | |||||
201338 | ERK-2 (pT185) | 201338 | P28482 | pT185 | |||||
201339 | Aurora kinase A (pT288) | 201339 | O14965 | pT288 | |||||
201340 | Aurora kinase B (pT232) | 201340 | Q96GD4 | pT232 | |||||
201341 | Aurora kinase C (pT198) | 201341 | Q9UQB9 | pT198 | |||||
201342 | S6 | 201342 | P62753 | 40S ribosomal protein S6, Phosphoprotein NP33 |