Binding affinity of 6 small molecule JAK inhibitors for 5 kinases - Dataset (ID:20369)

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Small Molecule target relation Kd
Alvocidib
DCLK3
=
1800
Nintedanib
DCLK3
=
90
Bosutinib
DCLK3
=
1900
Tofacitinib
DCLK3
=
7.1
Baricitinib
DCLK3
=
99
S-Ruxolitinib
DCLK3
=
220
Alvocidib
JAK1
>
10000
Nintedanib
JAK1
=
7800
Bosutinib
JAK1
>
10000
Tofacitinib
JAK1
=
0.55
Baricitinib
JAK1
=
0.38
S-Ruxolitinib
JAK1
=
3.4
Alvocidib
JAK2
=
6300
Nintedanib
JAK2
=
7.8
Bosutinib
JAK2
=
170
Tofacitinib
JAK2
=
0.58
Baricitinib
JAK2
=
0.047
S-Ruxolitinib
JAK2
=
0.18
Alvocidib
JAK3
=
1700
Nintedanib
JAK3
=
1.9
Bosutinib
JAK3
=
210
Tofacitinib
JAK3
=
0.11
Baricitinib
JAK3
=
0.97
S-Ruxolitinib
JAK3
=
2.4
Alvocidib
TYK2
=
320
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