LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist C in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20363)

Data Columns

  • 11 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
cell
Cell reagent
Cell cell
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
timepoint Timepoint Numeric 0
gR50
Small molecule concentration in uM at which GR(c)=0.5
GR50 Numeric 4
gRmax
Normalized growth inhibition rate at the highest tested concentration
GRmax Numeric 4
gRAOC
Integral of GR(c) over the range of concentrations tested
GR_AOC Numeric 4
gEC50
Small molecule concentration in uM that results in 50% efficacy
GEC50 Numeric 5
gRinf
Effect of the drug at infinite concentration
GRinf Numeric 4
hGR
GR Hill Coefficient of the fitted curve
h_GR Numeric 4
r2GR
r^2 for the sigmoidal curve fit to the dose-response data
r2_GR Numeric 4
pvalGR pval_GR Text
  • 11 Data Columns