LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vorinostat | 180622_MC_15 | 10287 | 0.0148 | 57 | 96 | 14 | 21 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_6 | 153 | 0.0147 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00941 | 0.7017 |
Vorinostat | 180622_MC_16 | 10661 | 0.0325 | 146 | 205 | 3 | 9 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 351 | 0.0319 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00781 | 0.7171 |
Vorinostat | 180622_MC_16 | 9849 | 0.0272 | 65 | 205 | 6 | 18 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_8 | 270 | 0.0267 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00261 | 0.6831 |
Vorinostat | 180622_MC_16 | 10838 | 0.0195 | 61 | 152 | 10 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_9 | 213 | 0.0193 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00479 | 0.7243 |
Vorinostat | 180622_MC_14 | 2245 | 0.0692 | 96 | 66 | 6 | 20 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_1 | 162 | 0.0673 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04324 | 0.1588 |
Vorinostat | 180622_MC_14 | 2309 | 0.0692 | 106 | 61 | 7 | 8 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 167 | 0.0674 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04338 | 0.1671 |
Vorinostat | 180622_MC_14 | 2418 | 0.0552 | 80 | 58 | 11 | 12 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_3 | 138 | 0.0540 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02992 | 0.1807 |
Vorinostat | 180622_MC_15 | 2903 | 0.0751 | 147 | 82 | 7 | 13 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_4 | 229 | 0.0731 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04905 | 0.2365 |
Vorinostat | 180622_MC_15 | 2721 | 0.0698 | 130 | 69 | 9 | 11 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_5 | 199 | 0.0682 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04408 | 0.2165 |
Vorinostat | 180622_MC_15 | 2741 | 0.0511 | 94 | 51 | 12 | 10 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_6 | 145 | 0.0502 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02617 | 0.2187 |
Vorinostat | 180622_MC_16 | 3333 | 0.0662 | 139 | 91 | 6 | 6 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_7 | 230 | 0.0646 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.04048 | 0.2804 |
Vorinostat | 180622_MC_16 | 3575 | 0.0518 | 135 | 57 | 9 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 192 | 0.0510 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02690 | 0.3032 |
Vorinostat | 180622_MC_16 | 3110 | 0.0589 | 131 | 60 | 10 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_9 | 191 | 0.0579 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03379 | 0.2582 |
Vorinostat | 180622_MC_14 | 1405 | 0.1149 | 118 | 57 | 10 | 16 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 175 | 0.1108 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.08669 | 0.0295 |
Vorinostat | 180622_MC_14 | 1337 | 0.1532 | 158 | 71 | 11 | 5 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_2 | 229 | 0.1462 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.12216 | 0.0167 |
Vorinostat | 180622_MC_14 | 1323 | 0.1486 | 137 | 80 | 13 | 5 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 217 | 0.1409 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.11684 | 0.0140 |
Vorinostat | 180622_MC_15 | 1473 | 0.1323 | 144 | 70 | 4 | 19 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_4 | 214 | 0.1269 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.10278 | 0.0419 |
Vorinostat | 180622_MC_15 | 1428 | 0.1260 | 136 | 61 | 5 | 17 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_5 | 197 | 0.1212 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.09716 | 0.0338 |
Vorinostat | 180622_MC_15 | 1500 | 0.1350 | 159 | 65 | 13 | 13 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_6 | 224 | 0.1299 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.10586 | 0.0467 |
Vorinostat | 180622_MC_16 | 1278 | 0.1390 | 139 | 58 | 10 | 4 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_7 | 197 | 0.1336 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.10949 | 0.0052 |
Vorinostat | 180622_MC_16 | 1367 | 0.1648 | 192 | 65 | 11 | 14 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_8 | 257 | 0.1583 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.13418 | 0.0224 |
Vorinostat | 180622_MC_16 | 1456 | 0.0934 | 107 | 39 | 12 | 16 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_9 | 146 | 0.0911 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06707 | 0.0388 |