Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| T47D | IU1 | 0.0316 | 1.0118 | -0.00638 |
| T47D | HY-17541A | 9.992797406 | 0.4289 | 0.14143 |
| T47D | SJB2-043 | 31.6 | -0.3821 | 0.54005 |
| T47D | GW7647 | 31.6 | 0.4054 | 0.12998 |
| T47D | Mitoxantrone | 0.099927974 | -0.0469 | 0.06301 |
| T47D | SB1-F-21 | 0.009992797 | 0.9588 | -0.00382 |
| T47D | SB1-F-22 | 9.992797406 | 0.9534 | -0.00396 |
| T47D | HY-17541A | 31.6 | -0.2976 | 0.44463 |
| T47D | z-VAE(OMe)-fmk | 0.999279741 | 1.0055 | -0.00708 |
| T47D | Trifluoperazine | 0.099927974 | 0.9991 | -0.00312 |
| T47D | PB49673382 | 0.0316 | 0.9457 | -0.00794 |
| T47D | GW7647 | 50.0 | -0.3773 | 0.61361 |
| T47D | IU1 | 50.0 | 0.5230 | 0.05598 |
| T47D | HY-50736 | 0.099927974 | 0.9474 | -0.00293 |
| T47D | IU1 | 3.16 | 1.0587 | -0.00968 |
| T47D | SB1-F-22 | 0.999279741 | 0.9548 | -0.00677 |
| T47D | HBX 41108 | 0.999279741 | 0.5112 | 0.21003 |
| T47D | Sepantronium | 9.992797406 | -0.5487 | 0.65344 |
| T47D | Doxycycline | 0.999279741 | 0.9257 | -0.00900 |
| T47D | IU1 | 31.6 | 0.7010 | -0.00760 |
| T47D | ML-323 | 0.316 | 0.9082 | -0.00581 |
| T47D | SB1-F-22 | 31.6 | 0.7134 | 0.00181 |
| T47D | HY-17541A | 50.0 | -0.5568 | 0.51640 |