Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-134-VI | Trifluoperazine | 31.6 | -0.8785 | 0.65027 |
| PDX1328 | b-AP15 | 3.16 | -0.8782 | 0.42865 |
| MDA-MB-134-VI | Mitoxantrone | 0.999279741 | -0.8709 | NaN |
| HCC202 | Trifluoperazine | 50.0 | -0.8634 | 0.20227 |
| PDX1328 | b-AP15 | 9.992797406 | -0.8632 | 0.45776 |
| MDA-MB-134-VI | SJB3-019A | 9.992797406 | -0.8622 | 0.66413 |
| PDX1328 | HBX 41108 | 31.6 | -0.8598 | 0.39720 |
| PDX1328 | Degrasyn | 9.992797406 | -0.8595 | 0.41878 |
| MDA-MB-361 | HY-17541A | 50.0 | -0.8457 | 0.49265 |
| BT-20 | HY-17541A | 50.0 | -0.8443 | 0.42063 |
| PDX1328 | HY-50736 | 9.992797406 | -0.8388 | 0.43911 |
| PDX1328 | HY-50737A | 3.16 | -0.8384 | 0.48654 |
| HCC1954 | HY-17541A | 31.6 | -0.8364 | 0.78437 |
| MDA-MB-134-VI | Sepantronium | 50.0 | -0.8332 | 0.47038 |
| BT-20 | Mitoxantrone | 9.992797406 | -0.8289 | 0.72348 |
| PDX1328 | Vialinin A | 50.0 | -0.8259 | 0.34615 |
| HCC1954 | HY-17541A | 50.0 | -0.8228 | 0.49114 |
| MDA-MB-134-VI | SJB3-019A | 31.6 | -0.8219 | 0.64274 |
| HCC1428 | HY-50736 | 0.999279741 | -0.8193 | 0.78464 |
| BT-20 | Mitoxantrone | 31.6 | -0.8192 | 0.59115 |
| MDA-MB-361 | Mitoxantrone | 9.992797406 | -0.8187 | 0.65149 |
| HCC1428 | P22077 | 50.0 | -0.8186 | 0.35751 |
| HCC1954 | P22077 | 31.6 | -0.8173 | 0.75139 |
| HCC202 | Trifluoperazine | 31.6 | -0.8172 | 0.72071 |
| SK-BR-3 | HY-17541A | 50.0 | -0.8127 | 0.59017 |