Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC202 | GW7647 | 3.16 | 1.3226 | 0.00740 |
| MDA-MB-134-VI | USP7-IN-1 | 0.0316 | 1.3241 | 0.00282 |
| MDA-MB-361 | STK547622 | 0.099927974 | 1.3249 | -0.00860 |
| BT-20 | IU1 | 9.992797406 | 1.3315 | -0.09598 |
| MDA-MB-361 | HBX19818 | 0.0316 | 1.3386 | 0.00168 |
| HCC1419 | Pevonedistat | 0.099927974 | 1.3392 | 0.01331 |
| Hs 578T | Doxycycline | 31.6 | 1.3436 | 0.03855 |
| HCC202 | GW7647 | 31.6 | 1.3473 | -0.00023 |
| HCC202 | USP7-IN-1 | 0.316 | 1.3535 | 0.01778 |
| MDA-MB-134-VI | MI-2 | 0.009992797 | 1.3588 | -0.00176 |
| HCC1954 | SJB2-043 | 0.316 | 1.3594 | 0.01934 |
| Hs 578T | Doxycycline | 50.0 | 1.3637 | -0.02647 |
| MDA-MB-134-VI | GW7647 | 3.16 | 1.3716 | -0.00711 |
| HCC1954 | HY-17542 | 0.0316 | 1.3883 | -0.00002 |
| BT-20 | IU1 | 3.16 | 1.3898 | -0.09162 |
| MDA-MB-361 | SJB2-043 | 0.00316 | 1.4230 | -0.00432 |
| MDA-MB-361 | IU1 | 9.992797406 | 1.4985 | -0.00373 |
| HCC1954 | P22077 | 0.009992797 | 1.5588 | -0.00976 |
| HCC1954 | Doxycycline | 9.992797406 | 1.8142 | 0.08673 |
| PDX1328 | SB1-F-22 | 0.999279741 | 2.0701 | -0.00837 |
| PDX1328 | Pevonedistat | 0.0316 | 2.2642 | -0.00673 |
| PDX1328 | Pevonedistat | 0.316 | 3.7848 | -0.04757 |
| PDX1328 | Pevonedistat | 0.099927974 | 4.1452 | -0.05106 |