Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| MDA-MB-361 | LDN57444 | 9.992797406 | 1.1108 | -0.00785 |
| PDXHCI002 | IU1 | 0.0316 | 1.1113 | -0.00841 |
| HCC202 | MI-2 | 0.009992797 | 1.1114 | 0.01831 |
| PDX1328 | z-VAE(OMe)-fmk | 50.0 | 1.1116 | -0.01964 |
| MDA-MB-231 | Spautin-1 | 3.16 | 1.1116 | -0.00371 |
| BT-20 | STK547622 | 3.16 | 1.1117 | -0.02493 |
| HCC1428 | HBX19818 | 0.316 | 1.1119 | -0.00024 |
| HCC1419 | GW7647 | 3.16 | 1.1125 | 0.00063 |
| CAMA-1 | USP7-IN-1 | 0.0316 | 1.1126 | -0.00023 |
| HCC1954 | HY-50736 | 0.009992797 | 1.1128 | 0.00309 |
| MDA-MB-361 | MI-2 | 0.099927974 | 1.1128 | -0.00230 |
| HCC202 | LDN57444 | 0.009992797 | 1.1134 | -0.00946 |
| MDA-MB-134-VI | HBX19818 | 0.316 | 1.1144 | -0.00121 |
| HCC1937 | 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one | 0.099927974 | 1.1151 | -0.00012 |
| HCC1954 | PB49673382 | 0.009992797 | 1.1154 | 0.00204 |
| HCC1500 | HY-17542 | 3.16 | 1.1154 | 0.01250 |
| MDA-MB-361 | P22077 | 0.316 | 1.1159 | -0.00502 |
| BT-20 | IU1 | 0.316 | 1.1162 | -0.04672 |
| HCC1937 | MI-2 | 0.009992797 | 1.1167 | 0.00479 |
| Hs 578T | SJB3-019A | 0.009992797 | 1.1172 | -0.01104 |
| HCC1428 | GW7647 | 0.999279741 | 1.1181 | -0.00798 |
| HCC1937 | GW7647 | 3.16 | 1.1181 | -0.00353 |
| MDA-MB-361 | IU1 | 0.009992797 | 1.1181 | -0.00714 |
| HCC1419 | MI-2 | 0.099927974 | 1.1186 | 0.00068 |
| MDA-MB-231 | Vialinin A | 0.999279741 | 1.1186 | -0.00299 |