Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1328 | Sepantronium | 3.16 | -0.9438 | 0.62771 |
| MDA-MB-134-VI | Mitoxantrone | 31.6 | -0.9383 | 0.71264 |
| PDX1328 | SJB2-043 | 0.999279741 | -0.9335 | 0.60610 |
| MDA-MB-134-VI | Mitoxantrone | 50.0 | -0.9303 | 0.66220 |
| MDA-MB-134-VI | HY-17541A | 50.0 | -0.9278 | 0.48000 |
| PDX1328 | SB1-F-21 | 9.992797406 | -0.9263 | 0.61803 |
| PDX1328 | Sepantronium | 0.999279741 | -0.9253 | 0.59365 |
| PDX1328 | HY-50737A | 9.992797406 | -0.9243 | 0.51091 |
| MDA-MB-361 | Mitoxantrone | 31.6 | -0.9240 | 0.78228 |
| PDX1328 | P22077 | 31.6 | -0.9192 | 0.50240 |
| PDX1328 | b-AP15 | 50.0 | -0.9168 | 0.32912 |
| PDX1328 | MI-2 | 50.0 | -0.9161 | 0.19119 |
| PDX1328 | HBX 41108 | 9.992797406 | -0.9112 | 0.56421 |
| PDX1328 | HY-50736 | 0.999279741 | -0.9100 | 0.56204 |
| PDX1328 | HY-50736 | 3.16 | -0.9094 | 0.53703 |
| PDX1328 | b-AP15 | 31.6 | -0.9086 | 0.49260 |
| PDX1328 | Degrasyn | 31.6 | -0.9056 | 0.53398 |
| PDX1328 | Sepantronium | 0.316 | -0.9020 | 0.56751 |
| PDX1328 | Pimozide | 31.6 | -0.8995 | 0.53187 |
| HCC1419 | Mitoxantrone | 31.6 | -0.8993 | 0.60636 |
| PDX1328 | Pimozide | 50.0 | -0.8952 | 0.52399 |
| PDX1328 | Degrasyn | 50.0 | -0.8901 | 0.33385 |
| PDX1328 | HY-50737A | 31.6 | -0.8890 | 0.43461 |
| BT-20 | HY-17541A | 31.6 | -0.8815 | 0.74454 |
| PDX1328 | MI-2 | 31.6 | -0.8808 | 0.52036 |