Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| SK-BR-3 | SJB2-043 | 31.6 | -0.6606 | 0.77162 |
| HCC1419 | Degrasyn | 31.6 | -0.7805 | 0.77162 |
| HCC1419 | HBX 41108 | 31.6 | -0.7549 | 0.77332 |
| Hs 578T | b-AP15 | 31.6 | -0.5434 | 0.77480 |
| SK-BR-3 | b-AP15 | 31.6 | -0.6425 | 0.77595 |
| HCC1428 | P22077 | 31.6 | -0.7838 | 0.77650 |
| HCC1428 | SJB3-019A | 50.0 | -0.7873 | 0.77657 |
| HCC1428 | HY-50737A | 0.999279741 | -0.7987 | 0.77706 |
| SK-BR-3 | b-AP15 | 9.992797406 | -0.6663 | 0.77748 |
| HCC1419 | b-AP15 | 9.992797406 | -0.7407 | 0.77887 |
| HCC1428 | SJB3-019A | 9.992797406 | -0.7761 | 0.77928 |
| HCC1806 | MI-2 | 31.6 | -0.5803 | 0.77940 |
| Hs 578T | Mitoxantrone | 3.16 | -0.5719 | 0.78047 |
| MDA-MB-361 | Mitoxantrone | 31.6 | -0.9240 | 0.78228 |
| HCC1954 | HY-17541A | 31.6 | -0.8364 | 0.78437 |
| HCC1428 | HY-50736 | 0.999279741 | -0.8193 | 0.78464 |
| MDA-MB-361 | Mitoxantrone | 50.0 | -0.9488 | 0.78637 |
| SK-BR-3 | SJB2-043 | 9.992797406 | -0.6773 | 0.78916 |
| SK-BR-3 | Sepantronium | 31.6 | -0.6755 | 0.79210 |
| SK-BR-3 | SJB3-019A | 0.999279741 | -0.6915 | 0.79312 |
| SK-BR-3 | SJB3-019A | 31.6 | -0.6743 | 0.79372 |
| SK-BR-3 | MI-2 | 3.16 | -0.5905 | 0.79580 |
| SK-BR-3 | SJB3-019A | 9.992797406 | -0.7024 | 0.79799 |
| HCC1428 | SJB3-019A | 3.16 | -0.8040 | 0.80308 |
| CAMA-1 | Mitoxantrone | 9.992797406 | -0.7131 | 0.80627 |