Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1937 | z-VAE(OMe)-fmk | 3.16 | 1.0194 | -0.00911 |
| HCC1937 | z-VAE(OMe)-fmk | 9.992797406 | 1.0028 | -0.00348 |
| HCC1937 | z-VAE(OMe)-fmk | 31.6 | 0.9933 | 0.01754 |
| HCC1937 | z-VAE(OMe)-fmk | 50.0 | 1.0663 | 0.03294 |
| HCC1954 | 1247825-37-1 | 0.009992797 | 0.9187 | 0.01654 |
| HCC1954 | 1247825-37-1 | 0.0316 | 1.0577 | 0.00922 |
| HCC1954 | 1247825-37-1 | 0.099927974 | 0.9039 | 0.01379 |
| HCC1954 | 1247825-37-1 | 0.316 | 0.8888 | 0.00335 |
| HCC1954 | 1247825-37-1 | 0.999279741 | 0.8330 | 0.00845 |
| HCC1954 | 1247825-37-1 | 3.16 | 0.9164 | -0.00770 |
| HCC1954 | 1247825-37-1 | 9.992797406 | 0.4655 | 0.06164 |
| HCC1954 | 1247825-37-1 | 31.6 | -0.2049 | 0.29181 |
| HCC1954 | 1247825-37-1 | 50.0 | -0.1838 | 0.30857 |
| HCC1954 | b-AP15 | 0.009992797 | 0.9647 | 0.02977 |
| HCC1954 | b-AP15 | 0.0316 | 0.9014 | -0.00241 |
| HCC1954 | b-AP15 | 0.099927974 | 0.2254 | 0.19532 |
| HCC1954 | b-AP15 | 0.316 | -0.4829 | 0.59356 |
| HCC1954 | b-AP15 | 0.999279741 | -0.5946 | 0.62141 |
| HCC1954 | b-AP15 | 3.16 | -0.6868 | 0.66190 |
| HCC1954 | b-AP15 | 9.992797406 | -0.7413 | 0.72790 |
| HCC1954 | b-AP15 | 31.6 | -0.6975 | 0.70343 |
| HCC1954 | b-AP15 | 50.0 | -0.7172 | 0.71222 |
| HCC1954 | USP7-IN-1 | 0.009992797 | 0.9418 | -0.00112 |
| HCC1954 | USP7-IN-1 | 0.0316 | 0.9410 | 0.00783 |
| HCC1954 | USP7-IN-1 | 0.099927974 | 1.0205 | 0.01358 |