Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
HCC1806 Pimozide
0.0316
 0.9858 -0.00071
HCC1806 Pimozide
0.099927974
 0.9945 0.00298
HCC1806 Pimozide
0.316
 0.9743 -0.00344
HCC1806 Pimozide
0.999279741
 1.0191 -0.00312
HCC1806 Pimozide
3.16
 0.9693 -0.00055
HCC1806 Pimozide
9.992797406
 0.6810 0.01433
HCC1806 Pimozide
31.6
 -0.4151 0.62795
HCC1806 Pimozide
50.0
 -0.4227 0.62877
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9587 -0.00161
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.9952 -0.00099
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 0.9943 0.00185
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 0.9904 0.00100
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9970 0.00137
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9625 0.00183
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9785 0.00039
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9460 0.00083
HCC1806 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 0.9889 0.00171
HCC1806 SB1-F-21
0.009992797
 0.9676 -0.00052
HCC1806 SB1-F-21
0.0316
 1.0137 0.00018
HCC1806 SB1-F-21
0.099927974
 0.9670 -0.00163
HCC1806 SB1-F-21
0.316
 0.9162 0.00349
HCC1806 SB1-F-21
0.999279741
 0.8304 0.01995
HCC1806 SB1-F-21
3.16
 0.2310 0.29065
HCC1806 SB1-F-21
9.992797406
 -0.4744 0.55513
HCC1806 SB1-F-21
31.6
 -0.5036 0.65237