Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1806 | MI-2 | 3.16 | 0.7302 | 0.20248 |
| HCC1806 | MI-2 | 9.992797406 | -0.4788 | 0.75818 |
| HCC1806 | MI-2 | 31.6 | -0.5803 | 0.77940 |
| HCC1806 | MI-2 | 50.0 | -0.5443 | 0.54937 |
| HCC1806 | Mitoxantrone | 0.009992797 | 0.9252 | 0.04385 |
| HCC1806 | Mitoxantrone | 0.0316 | 0.6117 | 0.16023 |
| HCC1806 | Mitoxantrone | 0.099927974 | 0.1499 | 0.18776 |
| HCC1806 | Mitoxantrone | 0.316 | 0.0030 | 0.20979 |
| HCC1806 | Mitoxantrone | 0.999279741 | -0.0421 | 0.40886 |
| HCC1806 | Mitoxantrone | 3.16 | -0.1969 | 0.60273 |
| HCC1806 | Mitoxantrone | 9.992797406 | -0.3416 | 0.47798 |
| HCC1806 | Mitoxantrone | 31.6 | -0.2704 | 0.43495 |
| HCC1806 | Mitoxantrone | 50.0 | -0.1445 | 0.19164 |
| HCC1806 | ML-323 | 0.009992797 | 0.9605 | -0.00256 |
| HCC1806 | ML-323 | 0.0316 | 1.0204 | -0.00202 |
| HCC1806 | ML-323 | 0.099927974 | 0.9991 | 0.00186 |
| HCC1806 | ML-323 | 0.316 | 1.0082 | -0.00045 |
| HCC1806 | ML-323 | 0.999279741 | 0.9839 | -0.00382 |
| HCC1806 | ML-323 | 3.16 | 0.9008 | 0.00796 |
| HCC1806 | ML-323 | 9.992797406 | 0.8423 | 0.00287 |
| HCC1806 | ML-323 | 31.6 | 0.6185 | 0.01197 |
| HCC1806 | ML-323 | 50.0 | 0.5104 | 0.01497 |
| HCC1806 | Pevonedistat | 0.009992797 | 0.9161 | 0.05296 |
| HCC1806 | Pevonedistat | 0.0316 | 0.5302 | 0.14201 |
| HCC1806 | Pevonedistat | 0.099927974 | -0.0325 | 0.33929 |