Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| BT-20 | MI-2 | 50.0 | -0.7289 | 0.39052 |
| BT-20 | Mitoxantrone | 0.009992797 | 0.2259 | 0.10851 |
| BT-20 | Mitoxantrone | 0.0316 | -0.0397 | 0.17737 |
| BT-20 | Mitoxantrone | 0.099927974 | -0.1812 | 0.25503 |
| BT-20 | Mitoxantrone | 0.316 | -0.3074 | 0.36994 |
| BT-20 | Mitoxantrone | 0.999279741 | -0.3498 | 0.48969 |
| BT-20 | Mitoxantrone | 3.16 | -0.6046 | 0.69051 |
| BT-20 | Mitoxantrone | 9.992797406 | -0.8289 | 0.72348 |
| BT-20 | Mitoxantrone | 31.6 | -0.8192 | 0.59115 |
| BT-20 | Mitoxantrone | 50.0 | -0.6195 | 0.11318 |
| BT-20 | ML-323 | 0.009992797 | 1.0183 | -0.01563 |
| BT-20 | ML-323 | 0.0316 | 0.9694 | 0.00510 |
| BT-20 | ML-323 | 0.099927974 | 0.9503 | -0.00282 |
| BT-20 | ML-323 | 0.316 | 1.0155 | -0.00315 |
| BT-20 | ML-323 | 0.999279741 | 0.9504 | -0.00398 |
| BT-20 | ML-323 | 3.16 | 0.8772 | -0.00827 |
| BT-20 | ML-323 | 9.992797406 | 0.9554 | -0.04435 |
| BT-20 | ML-323 | 31.6 | 0.7760 | -0.05876 |
| BT-20 | ML-323 | 50.0 | 0.7311 | -0.07119 |
| BT-20 | Pevonedistat | 0.009992797 | 1.0455 | 0.00847 |
| BT-20 | Pevonedistat | 0.0316 | 0.9710 | 0.00521 |
| BT-20 | Pevonedistat | 0.099927974 | 1.0430 | -0.01696 |
| BT-20 | Pevonedistat | 0.316 | 0.7972 | -0.00849 |
| BT-20 | Pevonedistat | 0.999279741 | 0.3731 | 0.03289 |
| BT-20 | Pevonedistat | 3.16 | -0.0165 | 0.12928 |