Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1500 | b-AP15 | 0.0316 | 1.0024 | -0.01332 |
| HCC1500 | b-AP15 | 0.099927974 | 0.8462 | 0.06535 |
| HCC1500 | b-AP15 | 0.316 | -0.1477 | 0.41348 |
| HCC1500 | b-AP15 | 0.999279741 | -0.4587 | 0.53622 |
| HCC1500 | b-AP15 | 3.16 | -0.5099 | 0.50613 |
| HCC1500 | b-AP15 | 9.992797406 | -0.5684 | 0.57588 |
| HCC1500 | b-AP15 | 31.6 | -0.5575 | 0.51620 |
| HCC1500 | b-AP15 | 50.0 | -0.5813 | 0.54352 |
| HCC1500 | USP7-IN-1 | 0.009992797 | 0.9750 | 0.00142 |
| HCC1500 | USP7-IN-1 | 0.0316 | 1.1225 | -0.00335 |
| HCC1500 | USP7-IN-1 | 0.099927974 | 0.9590 | 0.00128 |
| HCC1500 | USP7-IN-1 | 0.316 | 1.0425 | 0.04681 |
| HCC1500 | USP7-IN-1 | 0.999279741 | 0.8375 | 0.00751 |
| HCC1500 | USP7-IN-1 | 3.16 | 0.9816 | 0.01621 |
| HCC1500 | USP7-IN-1 | 9.992797406 | 0.8847 | 0.00983 |
| HCC1500 | USP7-IN-1 | 31.6 | 0.7439 | 0.04969 |
| HCC1500 | USP7-IN-1 | 50.0 | 0.4861 | 0.01497 |
| HCC1500 | Doxycycline | 0.009992797 | 0.7649 | 0.02612 |
| HCC1500 | Doxycycline | 0.0316 | 0.9106 | -0.01009 |
| HCC1500 | Doxycycline | 0.099927974 | 0.9602 | 0.00707 |
| HCC1500 | Doxycycline | 0.316 | 0.9803 | -0.00937 |
| HCC1500 | Doxycycline | 0.999279741 | 0.9322 | -0.00534 |
| HCC1500 | Doxycycline | 3.16 | 0.8966 | -0.00392 |
| HCC1500 | Doxycycline | 9.992797406 | 0.8413 | 0.16728 |
| HCC1500 | Doxycycline | 31.6 | 0.1964 | 0.42185 |