Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| HCC1428 | USP7-IN-1 | 3.16 | 1.0050 | 0.00291 |
| HCC1428 | USP7-IN-1 | 9.992797406 | 0.8941 | -0.00471 |
| HCC1428 | USP7-IN-1 | 31.6 | 0.9517 | -0.00091 |
| HCC1428 | USP7-IN-1 | 50.0 | 0.6846 | 0.05085 |
| HCC1428 | Doxycycline | 0.009992797 | 0.6610 | 0.01945 |
| HCC1428 | Doxycycline | 0.0316 | 0.9154 | -0.01356 |
| HCC1428 | Doxycycline | 0.099927974 | 1.0349 | -0.00701 |
| HCC1428 | Doxycycline | 0.316 | 0.8744 | -0.00631 |
| HCC1428 | Doxycycline | 0.999279741 | 0.9431 | -0.00970 |
| HCC1428 | Doxycycline | 3.16 | 0.7709 | -0.01300 |
| HCC1428 | Doxycycline | 9.992797406 | 0.8494 | -0.00174 |
| HCC1428 | Doxycycline | 31.6 | 0.6362 | 0.01315 |
| HCC1428 | Doxycycline | 50.0 | 0.5312 | 0.08703 |
| HCC1428 | GW7647 | 0.009992797 | 0.9440 | -0.00277 |
| HCC1428 | GW7647 | 0.0316 | 1.0062 | -0.00429 |
| HCC1428 | GW7647 | 0.099927974 | 0.8999 | -0.00544 |
| HCC1428 | GW7647 | 0.316 | 0.9005 | -0.00636 |
| HCC1428 | GW7647 | 0.999279741 | 1.1181 | -0.00798 |
| HCC1428 | GW7647 | 3.16 | 1.1817 | -0.00021 |
| HCC1428 | GW7647 | 9.992797406 | 1.0433 | 0.00034 |
| HCC1428 | GW7647 | 31.6 | 0.9243 | -0.00316 |
| HCC1428 | GW7647 | 50.0 | 0.6988 | 0.06034 |
| HCC1428 | HBX19818 | 0.009992797 | 0.9159 | -0.00816 |
| HCC1428 | HBX19818 | 0.0316 | 0.9508 | -0.00378 |
| HCC1428 | HBX19818 | 0.099927974 | 0.9096 | 0.00623 |