Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| SK-BR-3 | Sepantronium | 50.0 | -0.6896 | 0.53482 |
| SK-BR-3 | z-VAE(OMe)-fmk | 0.009992797 | 0.9580 | 0.00621 |
| SK-BR-3 | z-VAE(OMe)-fmk | 0.0316 | 0.9435 | 0.00045 |
| SK-BR-3 | z-VAE(OMe)-fmk | 0.099927974 | 0.9299 | 0.00248 |
| SK-BR-3 | z-VAE(OMe)-fmk | 0.316 | 1.0072 | 0.00442 |
| SK-BR-3 | z-VAE(OMe)-fmk | 0.999279741 | 0.9177 | 0.00152 |
| SK-BR-3 | z-VAE(OMe)-fmk | 3.16 | 1.0303 | -0.00129 |
| SK-BR-3 | z-VAE(OMe)-fmk | 9.992797406 | 0.9058 | -0.00075 |
| SK-BR-3 | z-VAE(OMe)-fmk | 31.6 | 0.9674 | 0.00516 |
| SK-BR-3 | z-VAE(OMe)-fmk | 50.0 | 0.9573 | -0.00343 |
| T47D | 1247825-37-1 | 0.009992797 | 0.9858 | -0.00622 |
| T47D | 1247825-37-1 | 0.0316 | 1.0889 | -0.00787 |
| T47D | 1247825-37-1 | 0.099927974 | 0.9485 | -0.00418 |
| T47D | 1247825-37-1 | 0.316 | 0.9992 | -0.00405 |
| T47D | 1247825-37-1 | 0.999279741 | 1.0257 | -0.00794 |
| T47D | 1247825-37-1 | 3.16 | 0.9377 | -0.00460 |
| T47D | 1247825-37-1 | 9.992797406 | 0.6904 | -0.00014 |
| T47D | 1247825-37-1 | 31.6 | -0.2221 | 0.25928 |
| T47D | 1247825-37-1 | 50.0 | -0.1799 | 0.25896 |
| T47D | b-AP15 | 0.009992797 | 1.0106 | -0.00412 |
| T47D | b-AP15 | 0.0316 | 1.0256 | 0.00038 |
| T47D | b-AP15 | 0.099927974 | 0.8159 | 0.13588 |
| T47D | b-AP15 | 0.316 | -0.2141 | 0.36782 |
| T47D | b-AP15 | 0.999279741 | -0.2579 | 0.24281 |
| T47D | b-AP15 | 3.16 | -0.1927 | 0.35976 |