Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
SK-BR-3 Pimozide
31.6
 -0.5466 0.70487
SK-BR-3 Pimozide
50.0
 -0.5520 0.74507
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9238 0.00459
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.9877 0.00451
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.0178 0.00448
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 1.0656 0.00409
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.8978 0.00342
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 0.9388 -0.00048
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9239 0.00525
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 0.9496 0.00268
SK-BR-3 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.0058 -0.00133
SK-BR-3 SB1-F-21
0.009992797
 0.9784 -0.00214
SK-BR-3 SB1-F-21
0.0316
 1.0195 0.00855
SK-BR-3 SB1-F-21
0.099927974
 0.7627 0.01679
SK-BR-3 SB1-F-21
0.316
 0.4278 0.10003
SK-BR-3 SB1-F-21
0.999279741
 -0.0370 0.25885
SK-BR-3 SB1-F-21
3.16
 -0.2035 0.46683
SK-BR-3 SB1-F-21
9.992797406
 -0.3508 0.51418
SK-BR-3 SB1-F-21
31.6
 -0.4562 0.57200
SK-BR-3 SB1-F-21
50.0
 -0.4487 0.37939
SK-BR-3 SB1-F-22
0.009992797
 0.9926 0.00233
SK-BR-3 SB1-F-22
0.0316
 1.0371 -0.00105
SK-BR-3 SB1-F-22
0.099927974
 1.0797 0.00135
SK-BR-3 SB1-F-22
0.316
 0.9639 0.00516
SK-BR-3 SB1-F-22
0.999279741
 0.9364 0.00536