Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 0.099927974 | -0.0242 | 0.28437 |
| SK-BR-3 | Mitoxantrone | 0.316 | -0.1438 | 0.36335 |
| SK-BR-3 | Mitoxantrone | 0.999279741 | -0.2272 | 0.39231 |
| SK-BR-3 | Mitoxantrone | 3.16 | -0.4635 | 0.69448 |
| SK-BR-3 | Mitoxantrone | 9.992797406 | -0.7151 | 0.84844 |
| SK-BR-3 | Mitoxantrone | 31.6 | -0.7263 | 0.83766 |
| SK-BR-3 | Mitoxantrone | 50.0 | -0.5391 | 0.66187 |
| SK-BR-3 | ML-323 | 0.009992797 | 1.0430 | 0.00015 |
| SK-BR-3 | ML-323 | 0.0316 | 0.9670 | 0.00302 |
| SK-BR-3 | ML-323 | 0.099927974 | 1.0215 | -0.00140 |
| SK-BR-3 | ML-323 | 0.316 | 0.9932 | 0.00067 |
| SK-BR-3 | ML-323 | 0.999279741 | 0.9296 | 0.01121 |
| SK-BR-3 | ML-323 | 3.16 | 0.9285 | 0.00588 |
| SK-BR-3 | ML-323 | 9.992797406 | 0.9330 | 0.01382 |
| SK-BR-3 | ML-323 | 31.6 | 0.7079 | 0.03581 |
| SK-BR-3 | ML-323 | 50.0 | 0.6083 | 0.03301 |
| SK-BR-3 | Pevonedistat | 0.009992797 | 0.9688 | 0.01762 |
| SK-BR-3 | Pevonedistat | 0.0316 | 0.7926 | 0.06005 |
| SK-BR-3 | Pevonedistat | 0.099927974 | 0.4386 | 0.11465 |
| SK-BR-3 | Pevonedistat | 0.316 | 0.1824 | 0.12787 |
| SK-BR-3 | Pevonedistat | 0.999279741 | 0.0587 | 0.13766 |
| SK-BR-3 | Pevonedistat | 3.16 | 0.0532 | 0.12481 |
| SK-BR-3 | Pevonedistat | 9.992797406 | 0.0760 | 0.09811 |
| SK-BR-3 | Pevonedistat | 31.6 | 0.0478 | 0.11613 |
| SK-BR-3 | Pevonedistat | 50.0 | 0.0282 | 0.03142 |