Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Mean Normalized Growth Rate Inhibition (GR) Value | Increased Fraction Dead |
|---|---|---|---|---|
| PDX1328 | z-VAE(OMe)-fmk | 0.009992797 | 1.0192 | -0.00787 |
| PDX1328 | z-VAE(OMe)-fmk | 0.0316 | 0.9740 | -0.00442 |
| PDX1328 | z-VAE(OMe)-fmk | 0.099927974 | 1.0958 | -0.00387 |
| PDX1328 | z-VAE(OMe)-fmk | 0.316 | 0.9415 | 0.00148 |
| PDX1328 | z-VAE(OMe)-fmk | 0.999279741 | 0.7756 | 0.00431 |
| PDX1328 | z-VAE(OMe)-fmk | 3.16 | 0.9526 | -0.00628 |
| PDX1328 | z-VAE(OMe)-fmk | 9.992797406 | 0.9702 | -0.01055 |
| PDX1328 | z-VAE(OMe)-fmk | 31.6 | 1.0551 | 0.01017 |
| PDX1328 | z-VAE(OMe)-fmk | 50.0 | 1.1116 | -0.01964 |
| PDXHCI002 | 1247825-37-1 | 0.009992797 | 1.1210 | -0.00505 |
| PDXHCI002 | 1247825-37-1 | 0.0316 | 1.0674 | -0.00633 |
| PDXHCI002 | 1247825-37-1 | 0.099927974 | 1.0194 | -0.00739 |
| PDXHCI002 | 1247825-37-1 | 0.316 | 0.9838 | 0.00770 |
| PDXHCI002 | 1247825-37-1 | 0.999279741 | 1.0587 | -0.01007 |
| PDXHCI002 | 1247825-37-1 | 3.16 | 0.9512 | 0.00622 |
| PDXHCI002 | 1247825-37-1 | 9.992797406 | 0.2503 | 0.10105 |
| PDXHCI002 | 1247825-37-1 | 31.6 | -0.2470 | 0.19162 |
| PDXHCI002 | 1247825-37-1 | 50.0 | -0.2501 | 0.22140 |
| PDXHCI002 | b-AP15 | 0.009992797 | 1.0094 | 0.03069 |
| PDXHCI002 | b-AP15 | 0.0316 | 0.5901 | 0.10842 |
| PDXHCI002 | b-AP15 | 0.099927974 | 0.1313 | 0.25428 |
| PDXHCI002 | b-AP15 | 0.316 | -0.3625 | 0.43634 |
| PDXHCI002 | b-AP15 | 0.999279741 | -0.3767 | 0.49984 |
| PDXHCI002 | b-AP15 | 3.16 | -0.4731 | 0.56314 |
| PDXHCI002 | b-AP15 | 9.992797406 | -0.4899 | 0.62989 |