Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20350)

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Cell Small Molecule Small Mol Concentration (uM) Mean Normalized Growth Rate Inhibition (GR) Value Increased Fraction Dead
MDA-MB-231 PB49673382
9.992797406
 0.3601 0.07532
MDA-MB-231 PB49673382
31.6
 0.0056 0.11738
MDA-MB-231 PB49673382
50.0
 -0.0627 0.17323
MDA-MB-231 Pimozide
0.009992797
 1.0742 -0.00085
MDA-MB-231 Pimozide
0.0316
 1.0717 -0.00034
MDA-MB-231 Pimozide
0.099927974
 0.9419 -0.00301
MDA-MB-231 Pimozide
0.316
 0.8752 0.00491
MDA-MB-231 Pimozide
0.999279741
 0.9087 0.00755
MDA-MB-231 Pimozide
3.16
 0.7743 0.01863
MDA-MB-231 Pimozide
9.992797406
 0.6363 0.05451
MDA-MB-231 Pimozide
31.6
 -0.2365 0.30642
MDA-MB-231 Pimozide
50.0
 -0.3159 0.46908
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.009992797
 0.9808 0.00140
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.0316
 0.6780 0.06627
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.099927974
 1.0005 0.00217
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.316
 0.9829 0.00489
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
0.999279741
 0.9625 -0.00343
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
3.16
 1.0305 0.00524
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
9.992797406
 0.9517 -0.00236
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
31.6
 1.0514 -0.00053
MDA-MB-231 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one
50.0
 1.0549 0.00163
MDA-MB-231 SB1-F-21
0.009992797
 1.0060 -0.00207
MDA-MB-231 SB1-F-21
0.0316
 1.0388 0.00134
MDA-MB-231 SB1-F-21
0.099927974
 0.8870 0.01115
MDA-MB-231 SB1-F-21
0.316
 0.7120 0.02442