LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 89.69 | 11.9 | 0.0001 | 0.0001 | -0.3321 | -0.7000 | 4.9958 | 1.5687 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 11.9 | Inf | Inf | -0.9909 | -0.8242 | 2.4551 | 1.5351 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 12.0 | Inf | Inf | -0.9704 | -0.7957 | 2.4990 | 1.5206 |
| MCF 10A-H2B-mCherry | Taxol | 80.31 | 11.9 | 0.0 | 0.0002 | -1.0000 | -0.8852 | 0.6794 | 1.4491 |
| MCF 10A-H2B-mCherry | Etoposide | 89.69 | 11.9 | Inf | Inf | -0.7330 | -0.7330 | 0.0000 | 1.3084 |
| MCF 10A-H2B-mCherry | Taxol | 76.90 | 11.9 | 0.0001 | 0.0003 | -0.9743 | -0.6652 | 0.7092 | 1.2470 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 12.0 | Inf | Inf | -0.8811 | -0.8811 | 0.0000 | 1.1884 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 11.9 | Inf | Inf | -0.8878 | -0.8878 | 0.0000 | 1.1597 |
| MCF 10A-H2B-mCherry | Etoposide | 80.31 | 11.9 | Inf | Inf | -0.9514 | -0.9514 | 0.0000 | 1.1514 |
| MCF 10A-H2B-mCherry | Dasatinib | 89.69 | 11.9 | Inf | Inf | -0.9466 | -0.9466 | 0.0000 | 1.1164 |
| MCF 10A-H2B-mCherry | Etoposide | 76.90 | 11.9 | Inf | Inf | -0.8928 | -0.8928 | 0.0000 | 1.0768 |
| MCF 10A-H2B-mCherry | Alpelisib | 89.69 | 11.9 | Inf | Inf | -0.9954 | -0.9954 | 0.0000 | 1.0518 |
| MCF 10A-H2B-mCherry | Taxol | 73.49 | 11.9 | Inf | Inf | -0.8372 | -0.6518 | 0.5709 | 1.0513 |
| MCF 10A-H2B-mCherry | Etoposide | 73.49 | 11.9 | Inf | Inf | -0.6007 | -0.6007 | 0.0000 | 0.9782 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 11.9 | Inf | Inf | -0.9117 | -0.9117 | 0.0000 | 0.9543 |
| MCF 10A-H2B-mCherry | Taxol | 66.19 | 11.9 | 0.0015 | 0.0018 | -0.7264 | -0.5641 | 5.0000 | 0.9534 |
| MCF 10A-H2B-mCherry | Taxol | 57.67 | 11.9 | 0.0016 | 0.0019 | -0.7476 | -0.6006 | 5.0000 | 0.9487 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 12.0 | Inf | Inf | -0.8540 | -0.8540 | 0.0000 | 0.9401 |
| MCF 10A-H2B-mCherry | Taxol | 52.56 | 11.9 | 0.0012 | 0.0016 | -0.7607 | -0.5550 | 2.7936 | 0.9382 |
| MCF 10A-H2B-mCherry | Taxol | 42.33 | 11.9 | 0.0009 | 0.0013 | -0.6426 | -0.5128 | 2.3074 | 0.9302 |
| MCF 10A-H2B-mCherry | Taxol | 44.03 | 11.9 | 0.0009 | 0.0013 | -0.6620 | -0.5136 | 2.4572 | 0.9282 |
| MCF 10A-H2B-mCherry | Taxol | 67.89 | 11.9 | 0.0011 | 0.0016 | -0.4845 | -0.5264 | 3.3721 | 0.9248 |
| MCF 10A-H2B-mCherry | Taxol | 61.08 | 11.9 | 0.0014 | 0.0017 | -0.4542 | -0.5569 | 3.8012 | 0.9243 |
| MCF 10A-H2B-mCherry | Taxol | 47.45 | 11.9 | 0.001 | 0.0014 | -0.6791 | -0.5351 | 2.4484 | 0.9236 |
| MCF 10A-H2B-mCherry | Taxol | 45.74 | 11.9 | 0.001 | 0.0013 | -0.5327 | -0.4972 | 2.3910 | 0.9179 |