LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 20.19 | 11.9 | 1.0484 | 6.2551 | 0.0379 | -0.5651 | 0.6316 | 0.2770 |
| MCF 10A-H2B-mCherry | Dasatinib | 20.19 | 11.9 | 0.1745 | 0.6356 | 0.0392 | -0.1961 | 0.3732 | 0.4695 |
| MCF 10A-H2B-mCherry | Vorinostat | 20.19 | 11.9 | 0.6033 | 0.8014 | -0.3633 | -0.2584 | 1.6052 | 0.4060 |
| MCF 10A-H2B-mCherry | Alpelisib | 20.19 | 11.9 | Inf | Inf | 0.4666 | 0.4567 | 2.5000 | 0.1534 |
| MCF 10A-H2B-mCherry | Neratinib | 20.19 | 11.9 | 0.0265 | 0.0223 | -0.1108 | 0.1112 | 1.3534 | 0.5062 |
| MCF 10A-H2B-mCherry | Taxol | 20.19 | 11.9 | 0.0017 | 0.004 | -0.7188 | -0.6844 | 1.0554 | 0.8484 |
| MCF 10A-H2B-mCherry | Palbociclib | 20.19 | 11.9 | 0.1053 | 23.8386 | 0.1006 | -0.3621 | 0.3848 | 0.4707 |
| MCF 10A-H2B-mCherry | Neratinib | 21.90 | 11.9 | 0.0207 | 0.0191 | -0.1246 | 0.0444 | 1.2557 | 0.5569 |
| MCF 10A-H2B-mCherry | Alpelisib | 21.90 | 11.9 | Inf | Inf | 0.4426 | 0.4238 | 2.5000 | 0.1686 |
| MCF 10A-H2B-mCherry | Trametinib | 21.90 | 11.9 | 0.0013 | 0.0014 | 0.1822 | 0.2336 | 1.5224 | 0.6197 |
| MCF 10A-H2B-mCherry | Vorinostat | 21.90 | 11.9 | 0.5423 | 0.8664 | -0.2962 | -0.3081 | 1.5323 | 0.4241 |
| MCF 10A-H2B-mCherry | Etoposide | 21.90 | 11.9 | 0.6499 | 3.6752 | 0.0253 | -0.3594 | 0.7066 | 0.3075 |
| MCF 10A-H2B-mCherry | Dasatinib | 21.90 | 11.9 | 0.1528 | 0.2547 | 0.0327 | -0.0888 | 0.5237 | 0.4742 |
| MCF 10A-H2B-mCherry | Palbociclib | 21.90 | 11.9 | 0.1028 | 3.6973 | 0.0917 | -0.2900 | 0.4483 | 0.4878 |
| MCF 10A-H2B-mCherry | Taxol | 21.90 | 11.9 | 0.0015 | 0.0031 | -0.7607 | -0.6638 | 1.1472 | 0.8704 |
| MCF 10A-H2B-mCherry | Etoposide | 23.60 | 11.9 | 0.4333 | 0.3681 | 0.0325 | 0.0929 | 0.9623 | 0.3221 |
| MCF 10A-H2B-mCherry | Alpelisib | 23.60 | 11.9 | Inf | Inf | 0.5168 | 0.4975 | 2.5000 | 0.1285 |
| MCF 10A-H2B-mCherry | Vorinostat | 23.60 | 11.9 | 0.5562 | 0.8818 | -0.2455 | -0.3180 | 1.2379 | 0.4408 |
| MCF 10A-H2B-mCherry | Trametinib | 23.60 | 11.9 | 0.0013 | 0.0015 | 0.2225 | 0.1793 | 1.2585 | 0.6490 |
| MCF 10A-H2B-mCherry | Taxol | 23.60 | 11.9 | 0.0016 | 0.0029 | -0.7608 | -0.6627 | 1.5068 | 0.8837 |
| MCF 10A-H2B-mCherry | Dasatinib | 23.60 | 11.9 | 0.1781 | 0.1699 | 0.0396 | 0.0416 | 0.6705 | 0.4476 |
| MCF 10A-H2B-mCherry | Neratinib | 23.60 | 11.9 | 0.0306 | 0.0309 | -0.1485 | -0.0099 | 1.0173 | 0.5273 |
| MCF 10A-H2B-mCherry | Palbociclib | 23.60 | 11.9 | 0.1293 | 4.9077 | 0.0535 | -0.4107 | 0.6847 | 0.4909 |
| MCF 10A-H2B-mCherry | Trametinib | 25.30 | 11.9 | 0.0017 | 0.0014 | 0.1022 | 0.1419 | 1.1785 | 0.6613 |
| MCF 10A-H2B-mCherry | Taxol | 25.30 | 11.9 | 0.0017 | 0.0028 | -0.8322 | -0.6866 | 1.8062 | 0.8951 |