LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 11.9 | Inf | Inf | -0.9117 | -0.9117 | 0.0000 | 0.9543 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 12.0 | Inf | Inf | -0.8540 | -0.8540 | 0.0000 | 0.9401 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 12.0 | Inf | Inf | -0.8811 | -0.8811 | 0.0000 | 1.1884 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 11.9 | Inf | Inf | -0.9874 | -0.9874 | 0.0000 | 0.8979 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 12.0 | Inf | Inf | -0.9870 | -0.9870 | 0.0000 | 0.8881 |
| MCF 10A-H2B-mCherry | Neratinib | 85.43 | 12.0 | Inf | Inf | -0.8789 | -0.8789 | 0.0000 | 0.5982 |
| MCF 10A-H2B-mCherry | Neratinib | 85.43 | 11.9 | Inf | Inf | 0.1308 | 0.1308 | 0.0000 | 0.4931 |
| MCF 10A-H2B-mCherry | Trametinib | 85.43 | 11.9 | Inf | Inf | 0.0455 | 0.0455 | 0.0000 | 0.6300 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 11.9 | Inf | Inf | -0.9917 | -0.9933 | 0.6160 | 0.5482 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 11.9 | Inf | Inf | -0.8878 | -0.8878 | 0.0000 | 1.1597 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 12.0 | Inf | Inf | -0.9908 | -0.9912 | 0.5687 | 0.5120 |
| MCF 10A-H2B-mCherry | Vorinostat | 85.43 | 12.0 | Inf | Inf | 0.1293 | 0.1293 | 0.0000 | 0.6446 |
| MCF 10A-H2B-mCherry | Trametinib | 89.69 | 11.9 | Inf | Inf | -0.1007 | -0.1007 | 0.0000 | 0.7813 |
| MCF 10A-H2B-mCherry | Etoposide | 89.69 | 11.9 | Inf | Inf | -0.7330 | -0.7330 | 0.0000 | 1.3084 |
| MCF 10A-H2B-mCherry | Neratinib | 89.69 | 11.9 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | 0.5370 |
| MCF 10A-H2B-mCherry | Dasatinib | 89.69 | 11.9 | Inf | Inf | -0.9466 | -0.9466 | 0.0000 | 1.1164 |
| MCF 10A-H2B-mCherry | Palbociclib | 89.69 | 11.9 | Inf | Inf | -0.9796 | -0.9796 | 0.0000 | 0.6834 |
| MCF 10A-H2B-mCherry | Taxol | 89.69 | 11.9 | 0.0001 | 0.0001 | -0.3321 | -0.7000 | 4.9958 | 1.5687 |
| MCF 10A-H2B-mCherry | Alpelisib | 89.69 | 11.9 | Inf | Inf | -0.9954 | -0.9954 | 0.0000 | 1.0518 |
| MCF 10A-H2B-mCherry | Vorinostat | 89.69 | 11.9 | Inf | Inf | 0.5920 | 0.5920 | 0.0000 | 0.6243 |