LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
---|---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Vorinostat | 47.45 | 11.9 | 1.449 | 1.8444 | -0.1922 | -0.2247 | 2.0346 | 0.2603 |
MCF 10A-H2B-mCherry | Vorinostat | 49.15 | 11.9 | 1.5433 | 1.8836 | -0.1670 | -0.2035 | 2.2201 | 0.2379 |
MCF 10A-H2B-mCherry | Vorinostat | 50.86 | 11.9 | 1.6427 | 2.2275 | -0.1772 | -0.2769 | 2.5033 | 0.2296 |
MCF 10A-H2B-mCherry | Vorinostat | 52.56 | 11.9 | 1.7015 | 2.2119 | -0.2009 | -0.2374 | 3.2129 | 0.2049 |
MCF 10A-H2B-mCherry | Vorinostat | 54.25 | 11.9 | 2.1006 | 2.42 | -0.1151 | -0.1804 | 2.8861 | 0.1820 |
MCF 10A-H2B-mCherry | Vorinostat | 55.97 | 11.9 | 2.1119 | 2.3545 | -0.1381 | -0.1723 | 3.1644 | 0.1856 |
MCF 10A-H2B-mCherry | Vorinostat | 57.67 | 11.9 | 2.3384 | 2.6827 | -0.0950 | -0.1809 | 2.9370 | 0.1725 |
MCF 10A-H2B-mCherry | Vorinostat | 59.37 | 11.9 | 2.1848 | 2.392 | -0.0905 | -0.1195 | 2.4477 | 0.1781 |
MCF 10A-H2B-mCherry | Vorinostat | 61.08 | 11.9 | 2.3764 | 2.5438 | -0.1126 | -0.0963 | 2.3719 | 0.1658 |
MCF 10A-H2B-mCherry | Vorinostat | 62.78 | 11.9 | 2.7049 | 2.7752 | -0.0004 | -0.0435 | 2.2956 | 0.1473 |
MCF 10A-H2B-mCherry | Vorinostat | 64.49 | 11.9 | 3.3049 | 3.3509 | -0.1239 | -0.0516 | 5.0000 | 0.1317 |
MCF 10A-H2B-mCherry | Vorinostat | 66.19 | 11.9 | 3.8965 | 3.9966 | -0.0930 | -0.0813 | 5.0000 | 0.1174 |
MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 12.0 | Inf | Inf | -0.9870 | -0.9870 | 0.0000 | 0.8881 |
MCF 10A-H2B-mCherry | Neratinib | 85.43 | 12.0 | Inf | Inf | -0.8789 | -0.8789 | 0.0000 | 0.5982 |
MCF 10A-H2B-mCherry | Etoposide | 85.43 | 12.0 | Inf | Inf | -0.8811 | -0.8811 | 0.0000 | 1.1884 |
MCF 10A-H2B-mCherry | Taxol | 85.43 | 12.0 | Inf | Inf | -0.9704 | -0.7957 | 2.4990 | 1.5206 |
MCF 10A-H2B-mCherry | Vorinostat | 85.43 | 12.0 | Inf | Inf | 0.1293 | 0.1293 | 0.0000 | 0.6446 |
MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 12.0 | Inf | Inf | -0.8540 | -0.8540 | 0.0000 | 0.9401 |
MCF 10A-H2B-mCherry | Trametinib | 85.43 | 12.0 | Inf | Inf | 0.0802 | 0.0802 | 0.0000 | 0.6023 |
MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 12.0 | Inf | Inf | -0.9908 | -0.9912 | 0.5687 | 0.5120 |