LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 69.60 | 11.9 | 0.6006 | 1.0581 | -0.8627 | -0.8773 | 3.5601 | 0.3744 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 12.0 | Inf | Inf | -0.8540 | -0.8540 | 0.0000 | 0.9401 |
| MCF 10A-H2B-mCherry | Taxol | 73.49 | 11.9 | Inf | Inf | -0.8372 | -0.6518 | 0.5709 | 1.0513 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.90 | 11.9 | Inf | Inf | -0.8342 | -0.8342 | 0.0000 | 0.7051 |
| MCF 10A-H2B-mCherry | Taxol | 25.30 | 11.9 | 0.0017 | 0.0028 | -0.8322 | -0.6866 | 1.8062 | 0.8951 |
| MCF 10A-H2B-mCherry | Taxol | 27.00 | 11.9 | 0.0017 | 0.0026 | -0.8263 | -0.6759 | 2.0774 | 0.8946 |
| MCF 10A-H2B-mCherry | Dasatinib | 71.30 | 11.9 | Inf | Inf | -0.7768 | -0.7768 | 0.0000 | 0.4315 |
| MCF 10A-H2B-mCherry | Taxol | 28.71 | 11.9 | 0.0016 | 0.0024 | -0.7752 | -0.6453 | 2.1307 | 0.8888 |
| MCF 10A-H2B-mCherry | Neratinib | 66.19 | 11.9 | 0.3419 | 0.382 | -0.7691 | -0.3742 | 4.9998 | 0.3397 |
| MCF 10A-H2B-mCherry | Taxol | 23.60 | 11.9 | 0.0016 | 0.0029 | -0.7608 | -0.6627 | 1.5068 | 0.8837 |
| MCF 10A-H2B-mCherry | Taxol | 21.90 | 11.9 | 0.0015 | 0.0031 | -0.7607 | -0.6638 | 1.1472 | 0.8704 |
| MCF 10A-H2B-mCherry | Taxol | 52.56 | 11.9 | 0.0012 | 0.0016 | -0.7607 | -0.5550 | 2.7936 | 0.9382 |
| MCF 10A-H2B-mCherry | Taxol | 57.67 | 11.9 | 0.0016 | 0.0019 | -0.7476 | -0.6006 | 5.0000 | 0.9487 |
| MCF 10A-H2B-mCherry | Taxol | 30.41 | 11.9 | 0.0015 | 0.0022 | -0.7435 | -0.6127 | 2.1579 | 0.8791 |
| MCF 10A-H2B-mCherry | Etoposide | 89.69 | 11.9 | Inf | Inf | -0.7330 | -0.7330 | 0.0000 | 1.3084 |
| MCF 10A-H2B-mCherry | Neratinib | 59.37 | 11.9 | 0.3227 | 0.5545 | -0.7328 | -0.7073 | 1.5946 | 0.3292 |
| MCF 10A-H2B-mCherry | Alpelisib | 76.90 | 11.9 | Inf | Inf | -0.7311 | -0.7311 | 0.0000 | 0.2949 |
| MCF 10A-H2B-mCherry | Taxol | 66.19 | 11.9 | 0.0015 | 0.0018 | -0.7264 | -0.5641 | 5.0000 | 0.9534 |
| MCF 10A-H2B-mCherry | Taxol | 20.19 | 11.9 | 0.0017 | 0.004 | -0.7188 | -0.6844 | 1.0554 | 0.8484 |
| MCF 10A-H2B-mCherry | Dasatinib | 73.49 | 11.9 | Inf | Inf | -0.7187 | -0.7187 | 0.0000 | 0.6199 |
| MCF 10A-H2B-mCherry | Neratinib | 61.08 | 11.9 | 0.3193 | 0.4739 | -0.7166 | -0.5803 | 1.8981 | 0.3308 |
| MCF 10A-H2B-mCherry | Neratinib | 64.49 | 11.9 | 0.3607 | 0.4759 | -0.7163 | -0.5720 | 3.3539 | 0.3509 |
| MCF 10A-H2B-mCherry | Dasatinib | 69.60 | 11.9 | Inf | Inf | -0.7093 | -0.7093 | 0.0000 | 0.3803 |
| MCF 10A-H2B-mCherry | Taxol | 49.15 | 11.9 | 0.0011 | 0.0014 | -0.7087 | -0.4671 | 2.6462 | 0.8938 |
| MCF 10A-H2B-mCherry | Neratinib | 71.30 | 11.9 | Inf | Inf | -0.7067 | -0.7067 | 0.0000 | 0.3198 |