LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 67.89 | 11.9 | Inf | Inf | -0.6482 | -0.9446 | 0.2134 | 0.3543 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 11.9 | Inf | Inf | -0.9117 | -0.9117 | 0.0000 | 0.9543 |
| MCF 10A-H2B-mCherry | Dasatinib | 66.19 | 11.9 | 1.4145 | 4.3056 | -0.5860 | -0.9014 | 2.7702 | 0.3291 |
| MCF 10A-H2B-mCherry | Etoposide | 76.90 | 11.9 | Inf | Inf | -0.8928 | -0.8928 | 0.0000 | 1.0768 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 11.9 | Inf | Inf | -0.8878 | -0.8878 | 0.0000 | 1.1597 |
| MCF 10A-H2B-mCherry | Taxol | 80.31 | 11.9 | 0.0 | 0.0002 | -1.0000 | -0.8852 | 0.6794 | 1.4491 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 12.0 | Inf | Inf | -0.8811 | -0.8811 | 0.0000 | 1.1884 |
| MCF 10A-H2B-mCherry | Neratinib | 85.43 | 12.0 | Inf | Inf | -0.8789 | -0.8789 | 0.0000 | 0.5982 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.31 | 11.9 | Inf | Inf | -0.8783 | -0.8783 | 0.0000 | 0.8067 |
| MCF 10A-H2B-mCherry | Neratinib | 69.60 | 11.9 | 0.6006 | 1.0581 | -0.8627 | -0.8773 | 3.5601 | 0.3744 |
| MCF 10A-H2B-mCherry | Taxol | 15.08 | 11.9 | 0.0045 | 0.019 | -0.5767 | -0.8583 | 0.7179 | 0.6695 |
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 12.0 | Inf | Inf | -0.8540 | -0.8540 | 0.0000 | 0.9401 |
| MCF 10A-H2B-mCherry | Palbociclib | 59.37 | 11.9 | 1.8094 | 7.7655 | -0.1104 | -0.8492 | 0.8174 | 0.2344 |
| MCF 10A-H2B-mCherry | Dasatinib | 64.49 | 11.9 | 1.8515 | 4.5604 | -0.5153 | -0.8450 | 2.8465 | 0.2907 |
| MCF 10A-H2B-mCherry | Taxol | 16.79 | 11.9 | 0.0027 | 0.0126 | -0.6222 | -0.8419 | 0.7095 | 0.7366 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.90 | 11.9 | Inf | Inf | -0.8342 | -0.8342 | 0.0000 | 0.7051 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 11.9 | Inf | Inf | -0.9909 | -0.8242 | 2.4551 | 1.5351 |
| MCF 10A-H2B-mCherry | Dasatinib | 57.67 | 11.9 | 4.4368 | 6.0598 | -0.4485 | -0.8032 | 4.8913 | 0.2064 |
| MCF 10A-H2B-mCherry | Dasatinib | 62.78 | 11.9 | 2.0981 | 4.2239 | -0.4665 | -0.8011 | 2.9618 | 0.2741 |
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 12.0 | Inf | Inf | -0.9704 | -0.7957 | 2.4990 | 1.5206 |
| MCF 10A-H2B-mCherry | Dasatinib | 71.30 | 11.9 | Inf | Inf | -0.7768 | -0.7768 | 0.0000 | 0.4315 |
| MCF 10A-H2B-mCherry | Dasatinib | 59.37 | 11.9 | 4.4684 | 6.0639 | -0.4145 | -0.7730 | 5.0000 | 0.2216 |
| MCF 10A-H2B-mCherry | Neratinib | 37.23 | 11.9 | 0.1793 | 0.5696 | -0.4836 | -0.7708 | 0.8358 | 0.3897 |
| MCF 10A-H2B-mCherry | Dasatinib | 61.08 | 11.9 | 2.484 | 4.7737 | -0.4178 | -0.7602 | 3.0185 | 0.2572 |
| MCF 10A-H2B-mCherry | Dasatinib | 47.45 | 11.9 | 0.6525 | 4.8106 | -0.2148 | -0.7541 | 0.4818 | 0.3498 |