LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 55.97 | 11.9 | 0.0014 | 0.0017 | -0.6141 | -0.5226 | 3.9626 | 0.9101 |
| MCF 10A-H2B-mCherry | Taxol | 59.37 | 11.9 | 0.0014 | 0.0017 | -0.5953 | -0.4995 | 4.0561 | 0.9069 |
| MCF 10A-H2B-mCherry | Taxol | 62.78 | 11.9 | 0.0014 | 0.0017 | -0.6938 | -0.5140 | 4.2755 | 0.9151 |
| MCF 10A-H2B-mCherry | Palbociclib | 73.49 | 11.9 | 3.8592 | 5.0055 | -0.9830 | -1.0000 | 4.3323 | 0.1600 |
| MCF 10A-H2B-mCherry | Alpelisib | 25.30 | 11.9 | Inf | 2.7919 | 0.5162 | 0.5717 | 4.5032 | 0.1028 |
| MCF 10A-H2B-mCherry | Palbociclib | 76.90 | 11.9 | 3.8753 | 4.8812 | -0.9978 | -1.0000 | 4.7782 | 0.1974 |
| MCF 10A-H2B-mCherry | Dasatinib | 57.67 | 11.9 | 4.4368 | 6.0598 | -0.4485 | -0.8032 | 4.8913 | 0.2064 |
| MCF 10A-H2B-mCherry | Taxol | 89.69 | 11.9 | 0.0001 | 0.0001 | -0.3321 | -0.7000 | 4.9958 | 1.5687 |
| MCF 10A-H2B-mCherry | Neratinib | 66.19 | 11.9 | 0.3419 | 0.382 | -0.7691 | -0.3742 | 4.9998 | 0.3397 |
| MCF 10A-H2B-mCherry | Dasatinib | 59.37 | 11.9 | 4.4684 | 6.0639 | -0.4145 | -0.7730 | 5.0000 | 0.2216 |
| MCF 10A-H2B-mCherry | Alpelisib | 38.93 | 11.9 | Inf | 6.4483 | 0.6837 | 0.6427 | 5.0000 | 0.0115 |
| MCF 10A-H2B-mCherry | Vorinostat | 67.89 | 11.9 | 4.2349 | 4.3812 | -0.0390 | -0.0945 | 5.0000 | 0.1111 |
| MCF 10A-H2B-mCherry | Vorinostat | 66.19 | 11.9 | 3.8965 | 3.9966 | -0.0930 | -0.0813 | 5.0000 | 0.1174 |
| MCF 10A-H2B-mCherry | Palbociclib | 80.31 | 11.9 | 3.7073 | 4.6207 | -0.9998 | -1.0000 | 5.0000 | 0.2973 |
| MCF 10A-H2B-mCherry | Taxol | 57.67 | 11.9 | 0.0016 | 0.0019 | -0.7476 | -0.6006 | 5.0000 | 0.9487 |
| MCF 10A-H2B-mCherry | Taxol | 64.49 | 11.9 | 0.0016 | 0.0018 | -0.4233 | -0.4418 | 5.0000 | 0.8544 |
| MCF 10A-H2B-mCherry | Vorinostat | 69.60 | 11.9 | 4.6605 | 4.5982 | 0.1156 | 0.0327 | 5.0000 | 0.1150 |
| MCF 10A-H2B-mCherry | Alpelisib | 40.63 | 11.9 | Inf | 7.2456 | 0.7345 | 0.6596 | 5.0000 | 0.0088 |
| MCF 10A-H2B-mCherry | Vorinostat | 64.49 | 11.9 | 3.3049 | 3.3509 | -0.1239 | -0.0516 | 5.0000 | 0.1317 |
| MCF 10A-H2B-mCherry | Taxol | 66.19 | 11.9 | 0.0015 | 0.0018 | -0.7264 | -0.5641 | 5.0000 | 0.9534 |